哒嗪

计算结果表明：三种化合物分子内部HOMO到LU-MO电子跃迁，哒嗪的电子是由杂原子N向C原子转移，而吡嗪和嘧啶电子转移方向刚好相反；

The results show that the transition between HOMO and LUMO in the three compounds is the electronic transformation from hetero-atoms N to C in pyridazine while from C to N in pyrazine and pyrimidine .

介绍了咪唑并〔1,2-b〕哒嗪的合成方法、用途、生产及需求。

The preparation , application , production and demand of imidazo 〔 1,2-b 〕 pyridazine were introduced .

氨基-3（2H）-哒嗪酮合成研究进展

The synthesis development of amino-3 ( 2H ) - pyridazinone

6-苯基-4,5-二氢-3（2H）-哒嗪酮合成方法改进

Improved synthesis of 6-phenyl-4,5-dihydro-3 ( 2h ) - pyridazinones

4,5-二氢-3（2H）-哒嗪酮衍生物的合成及抑制血小板聚集作用

Syntheses and platelet aggregation inhibitory activity of 4,5-dihydro-3 ( 2 H ) - pyridazinones

设计并合成了6-（4-取代苯基）-5-甲基-4,5-二氢-3（2H）哒嗪酮类化合物。

The 6 - ( 4-substituted phenyl ) - 5-methyl-4,5-dihydro-3 ( 2H ) - pyridazinones were designed and synthesized .

6-（4-取代苯基）-4,5-二氢-3（2H）-哒嗪酮类化合物的合成及血小板聚集抑制作用

Synthesis and Platelet Aggregation Inhibitory Activity of 6 ( 4 Substituted Phenyl ) 4,5 Dihydro 3 ( 2 H ) Pyridazinones

6-取代苯基-3（2H）哒嗪酮的合成、抗惊活性及其构效关系的研究

Studies on synthesis , anticonvulsant activity and the structure & activity relationships of 6 - ( substituted phenyl ) - 3 ( 2h ) pyridazinones

6-[4-（4′-吡啶）氨基苯]-4,5-二氢-3（2H）哒嗪酮对大鼠胸主动脉环收缩功能的影响

Effects of 6 - [ 4 - ( 4 ′ - pyridyl ) amino-phenyl ] - 4,5-dihydro-3 ( 2H ) - pyridazinone on contraction of aorta in rats

6-取代苯基-3（2H）-哒嗪酮的合成（2）苯并咪唑2位侧链无间隔基毒性相对较低；

Synthesis of 6 - Substituted Phenyl - 3 ( 2 H ) - Pyridazinones ( 2 ) substituted phenyl at the C - 2 could reduce toxicity ;

6-[4-（4′-吡啶）氨基苯]-4,5-二氢-3（2H）哒嗪酮抗兔和大鼠失血性休克效应及初步机理

Therapeutic effect of 6 - [ 4 - ( 4 ′ - pyridyl ) aminophenyl ] - 4,5-dihydro-3 ( 2H ) - pyridazinone on hemorrhagic shock and its mechanisms in rabbits and rats

目的：设计合成一类6-（取代苯基）-4,5-二氢-3（2H）哒嗪酮类化合物，以期发现作用更强的血小板聚集抑制剂。

Objective : Analogues of 6 [ 4 ( 4 substituted piperazine ) phenyl ] 4,5 dihydro 3 ( 2 H ) pyridazinones is synthesized in search for more potent and selective antithrombotic drugs .

以3,6-二氯哒嗪为原料，经氨化、环合、脱氯得咪唑并〔1,2-b〕哒嗪。

Based on 3,6-dichloro pyridazine , imidazo 〔 1,2-b 〕 pyridazine was synthesized via amination , cyclization and dechlorination .

目的研究新型钙增敏强心剂6-[4-（4′-吡啶）氨基苯]-4,5-二氢-3（2H）哒嗪酮（MCI-154）的扩血管作用机制。

AIM To explore the mechanism of vasodilation effect of 6 - [ 4 - ( 4 ′ - pyridyl ) amino-phenyl ] - 4,5-dihydro-3 ( 2H ) - pyridazinone ( MCI-154 ), a novel calcium sensitizer for cardiac contraction protein .

咪唑并〔1,2-b〕哒嗪是合成头孢类抗生素的侧链中间体，因合成难度较大，成为国内开发头孢唑兰的瓶颈。

Imidazo 〔 1,2-b 〕 pyridazine is the main intermediate with side chain for synthesis of cephalosporins , it has become a bottle-necking problem for development of cefozopran as its greater difficulty in synthesis .

叙述了氟代哒嗪化合物合成方法学研究进展。

Researching progress on the synthesis methodology of fluoropyridazines is described .

3-芳氧基-6-取代哒嗪的合成及其除草活性

Synthesis and Herbicidal Activity of 3 - Aryloxy - 6-substituted Pyridazines

哒嗪酮类化合物的合成及其抗血小板聚集活性

Synthesis of pyridazinone derivatives and study of their antiplatelet aggregation activity

3-溴-6-甲基哒嗪的结构、光谱和热力学性质

The Conformation , Spectroscopy and Thermodynamic Properties of the 3-bromo-6-methyl Pyridoxine

6-羟基富烯及环戊二烯并[d]哒嗪的合成

Synthesis of 6 - Hydroxy Fulvenes and Cyclopenta [ d ] pyridazines

离子液体催化合成苯并哒嗪酮类葡萄糖苷化合物

Catalysis Synthesis of Benzo Pyridazinone Glucosidase Compounds under Ionic Liquid

手性方酰化双取代哒嗪的合成及荧光性研究

Synthesis and fluorescence of chiral disubstituted pyridazine of squaric acid

6-芳基-3-（4-取代哌嗪）哒嗪类化合物的合成及抗惊厥活性

Synthesis and anticonvulsant activity of 6-aryl-3 - ( 4-methylpiperazine ) - pyridazines

3-烷氧基-6-（4-甲苯基）哒嗪的合成及介晶性

Synthesis and liquid crystal behavior of 3-alkoxy-6 - ( 4-methylphenyl ) pyridazine

哒嗪类化合物9403诱导小麦雄性不育的初步研究

Male sterility induced by pyridazine compound 9403 in wheat

哒嗪-碘电荷转移复合物的导电性

Conductivity of charge transfer complex of pyridazine with iodine

哒嗪酮类α1-肾上腺素受体拮抗剂的合成和生物活性研究

Studies on Synthesis and Biological Activity of Pyridazinone Derivatives as α _1-Adrenoceptor Antagonist

简要综述哒嗪酮类化合物近年来的药用研究进展。

The recent progress in research on pyridazinone derivatives was summarized in this paper .

相转移催化合成6-4-（取代苯基）哒嗪酮类化合物

Synthesis of analogues of 6-4 - ( substituted phenyl ) pyridazinones by phase-transfer catalysis

咪唑并[1,2-b]哒嗪的制备

Preparation of Imidazo [ 1,2-b ] pyridazine