华蟾毒精
- 网络cinobufagin;cinobufaginol;Cinobufotalin
华蟾毒精-
目的了解中药成分华蟾毒精（cinobufagin，CBG）的体外抗癌活性及其主要作用机制。
AIM To explore anticancer activity and mechanism of Cinobufagin ( CBG ) in vitro .
-
华蟾毒精抗癌作用的体外研究
Experimental study on anticancer action of cinobufagin in vitro
-
方法：采用体外人肠内细菌粗酶与华蟾毒精和羟基华蟾毒精温孵法；
Methods : The cinobufagin and cinobufotalin were incubated with crude enzymes of human intestinal bacteria in vitro .
-
就抗肿瘤活性而言，华蟾毒精在人及常用实验动物（猴、狗、猪、大鼠、小鼠）中因代谢而失活。
The anticancer activities of cinobufagin would be reduced by the metabolism no matter in human or in monkey , dog , pig , rat and mouse .