半乳糖胺
- 网络galactosamine;GALN;D-GalN;D-galactosamine;GalNAc
![半乳糖胺](../cache/1173388.jpg)
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方法应用D-半乳糖胺腹腔注射诱导Wistar大鼠呈急性肝脏衰竭。
Methods : 30 Wistar rats were injected D galactosamine to induce AHF model .
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采用半乳糖胺(Galn)诱导大鼠肝硬化。
A liver cirrhosis model of rat was established by galactosamine ( Galn ) induction .
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朱砂莲提取物(A(1015))对D-氨基半乳糖胺肝损伤模型小鼠DNA合成作用的影响
The effect of A_ ( 1015 ) on DNA synthesis of D-galactosamine damaged mice hepatotoxicity
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结果用C(57)小鼠以半乳糖胺联用福氏全剂组肝损伤模型成型率最佳。
Results The results showed that the liver injury models were best Established using C_ ( 57 ) black mice with GalN Combined with FCA .
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新配方H和I还具有降低D-半乳糖胺诱发小鼠血清谷丙转氨酶升高的作用。
Bovis , artificial bovis , and new artificial prescription H , I also obviously decreased the elevated SGPT level in serum induced by DGLaN in mouse .
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为研究胡黄连提取物对四氯化碳(CCl4)或半乳糖胺(DGaIN)损伤原代培养大鼠肝实质细胞的保护作用。
The protective effect of the extracts of Rhizoma Picrorhizae on primary cultured hepatocytes injured by CCl 4 and D-GaIN was studied .
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方法以D-氨基半乳糖胺(D-gal)作为肝脏毒剂,构建雌性SD大鼠急性肝衰竭模型。
Methods A female rat model of liver injury induced by D-galactosamine ( D-gal ) was established .
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利用LPS联合D-半乳糖胺(LPS/D-GalN)给小鼠进行腹腔注射,可以诱导特异性的肝损伤产生,而对心、脾、肺等其他器官未造成明显损伤。
LPS in combination with D-GalN can induce specific liver injury , but has no effect on other organs , such as the heart , spleen and lung .
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方法:采用急性CCl4肝损伤模型、D-半乳糖胺盐酸盐大鼠急性肝损伤模型、ConA致小鼠急性肝损伤模型研究陆英颗粒灌胃给药对急性实验性肝损伤的保护作用。
Methods : The acute liver-injury model induced by CCl_4 or D-GalN or ConA was established in mice or rats .
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方法:雄性昆明小鼠,给予D-半乳糖胺(D-Gal-N)和脂多糖(LPS)同时腹腔注射,制备小鼠急性肝衰竭模型;
Method : Acute liver failure was induced in male Kunming strain mice by enterocoelia injecting the animals with D-Gal-N and LPS .
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结论以C57黑小鼠使用半乳糖胺辅以福氏全剂可以形成小鼠慢性免疫性肝损伤模型。
Conclusion liver injury models for mice can be established using C57 mice with GaIN Combined with FCA .
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【方法】选用四氯化碳(CCl4)和D-氨基半乳糖胺(D-Gal)致大鼠急性肝损伤模型,观察3个黄酮类化合物对血清丙氨酸转氨酶(ALT)、门冬氨酸转氨酶(AST)的影响;
[ Methods ] Acute hepatic injury models induced by CCl 4 and D-aminogalactose were used to investigate the effect of the three flavonoids on the serum AST and ALT levels ;
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方法:采用四氯化碳(CCl4)或D-半乳糖胺(D-GalN)所致肝损伤模型为研究对象,观察京玉清肝胶囊对实验性肝损伤的保护作用。
Methods : Taking liver-injured mice model induced by CCl_ ( 4 ) and D-galactamine ( D-GalN ) as the subject , to observe the related indexes .
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方法:分别采用D半乳糖胺(DGL)和四氯化碳(CCl4)诱导小鼠发生实验性急性肝损伤。
Method : Mouse acute liver injury model was induced by D galactosamine ( D GL ) or carbon tetrachloride ( CCl 4 ) .
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用经N-乙酰基-D-半乳糖胺-epoxy-sepharose6B亲和层析体系纯化的大豆凝集素制备兔抗大豆凝集素多克隆抗体,建立大豆凝集素间接抑制ELISA定量检测方法,检测下限低于10ng/mL。
Soybean agglutinin ( SBA ) was purified with GalNac-epoxy-sepharose 6B affinity chromatography systems , and polyclonal antibody of rabbit-anti-SBA was made . The way of quantitative determination of SBA with indirect inhibiting ELISA was established and the low limit was lower than 10 ng / mL.
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以D-半乳糖胺(500mg·kg~(-1))给予小鼠腹腔注射24~48h后,导致实验性肝病变,观察可见肝细胞组织酶反应减弱,超微结构严重受损。
The experimental hepatic lesion of mouse were induced by intraperitoneal injection of D-galactosamine ( 500mg · kg  ̄( - 1 )) . After 24  ̄ 48h , the reaction of RNA , DNA and succinic dehydrogenase ( SDHase ) of the cells were decreased and the ultrastructure were damaged .
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玉米肽对半乳糖胺诱导肝损伤小鼠的保护作用
Hepatoprotective Effects of Corn Peptides Against D-galactosamine-Induced Liver Injury in Mice
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谷氨酰胺防治半乳糖胺/脂多糖诱导急性肝损伤实验研究
The Effect of Glutamine on the Liver Injury by LPS
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消炎痛诱导大鼠肝脏对半乳糖胺损伤的保护作用
Indomethacin induced hepatic protection against galactosamine toxicity in rats
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D-半乳糖胺致急性肝损伤后大鼠胰岛细胞的免疫组织化学研究
Immunohistochemical Changes of Pancreatic Islet Cells following Acute Liver Injury Induced by D-galactosamine in Rats
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甘草酸二胺脂质复合物对D-半乳糖胺诱导小鼠肝损伤的保护作用
Protective effect of diammonium glycyrrhizinate phosphatidylcholine complex on D-galactosamine hydrochloride-induced acute liver injury in rats
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添加N-乙酰-D-半乳糖胺消除大豆凝集素抗营养活性的可行性研究
A Primary Research on the Elimination of Antinutritional Effect of Soybean Agglutinin by Adding N-acetyl-D-galactosamine
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这一结果表明大豆凝集素最理想的纯化方法是N-乙酰基-D-半乳糖胺-expoxy-sepharose6B亲和层析体系。
This result indicated that the best way to purify soybean agglutinin was GalNac-epoxy-Sepharose 6B .
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水芹总酚酸对D-半乳糖胺盐酸盐诱导肝损伤的保护作用
Protective Effect of Total Phenolics Acid of Oenanthe Javanica on Hepatic Injury Mice Induced By D-Galn
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双酶法制备的玉米肽对D-半乳糖胺致肝损伤小鼠的保护作用
Hepatoprotective Effects of Corn Peptides Prepared by Dual Enzyme Method on D-Galactosamine-induced Liver Injury in Mice
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成年雄性大鼠72只,分为盐水组和给药组(注射D-半乳糖胺)。
72 adult male rats were divided into 2 groups , i. e. control group and D-galactosamine administration group .
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马来酸二乙酯对半乳糖胺/脂多糖致小鼠急性肝损伤发生中核转录因子表达的影响
Diethyl maleate to influence the nuclear transcription factor expression in D-galactosamine / lipopolysaccharide induced acute liver injury in mice
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用N-乙酰基-D-半乳糖胺-epoxy-Sepharose6B、半乳糖胺-CH-Sepharose4B和瓜尔胶三种亲和层析体系对大豆中的凝集素进行分离提纯,并进行了多方面的比较。
Purification of soybean agglutinin with three affinity chromatography systems , GalNac-epoxy-Sepharose 6B , Gal-CH-Sepharose 4B and guar were compared .
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目的研究D-半乳糖胺和脂多糖导致大鼠急性肝衰竭的发病机理。
Objective To study the pathogenesis of D-galactosamine ( D-GalN ) - and lipopolysaccharides ( LPS ) - induced fulminant hepatic failure .
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人类N-乙酰半乳糖胺4-硫酸酯酶重组体在黏多糖病Ⅵ型(马-拉二综合征)患者替代疗法中的药物代谢动力学模式:一项Ⅰ/Ⅱ期研究
Pharmacokinetic profile of recombinant human N-acetylgalactosamine 4-sulphatase enzyme replacement therapy in patients with mucopolysaccharidosis VI ( Maroteaux-Lamy syndrome ): A phase I / II study