分化能力

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  • differentiative capacity
分化能力分化能力
  1. 淋巴细胞对电离辐射敏感,照射后不能修复被损害的DNA,失去增殖和分化能力,即使在受者体内存活也不会对机体产生免疫排斥和攻击。

    Lymphocytes are sensitive to gamma irradiation and lose their ability to proliferate and differentiate due to DNA damage after irradiation .

  2. 移植丧失分化能力的MSCs及正常MSCs都能明显改善心梗后早期的心功能。

    Both MSCs with or without the differentiation potency can improve cardiac function obviously after AMI .

  3. 观察细胞各个阶段的形态,通过生长曲线等手段研究骨骼肌卫星细胞的增殖与分化能力,利用RT-PCR以及免疫细胞化学染色对所获得的细胞进行鉴定。

    Morphological observation and growth curve were used to evaluate the proliferative and differentiation ability of skeletal muscle satellite cells .

  4. 目的:研究无糖处理对体外分离培养神经前体细胞(NeuralPrecursorCells,NPCs)的存活、分裂及分化能力的影响。

    Objective : To investigate the survival , division , and differentiation of neural precursor cells ( NPCs ) following glucose free treatment in vitro .

  5. bFGF、TGF-β对人牙髓干细胞增殖和分化能力的影响

    The effect of bFGF and TGF - β on the proliferation and differentiation of human dental pulp stem cell

  6. 方法从正常人骨髓中分离扩增MSC,通过免疫表型和向成骨细胞及脂肪细胞分化能力对其鉴定;

    Methods MSCs were obtained from human bone marrow and their differentiation function and phenotype were identified .

  7. 脐带血CD34+细胞及其亚群的增殖分化能力明显高于骨髓和外周血,可形成更多的各系造血集落和维持更长久的造血活动。

    More hematopoietic colony formation from cord blood than that from bone marrow or peripheral blood was observed .

  8. 成骨细胞特异性钙黏蛋白涂布脱钙骨基质材料对BMSCs黏附及成骨分化能力的影响

    Effects of demineralized bone matrix modified with type II cadherin ectodomain on adhesion and osteogenic differentiation of BMSCs

  9. 通过对骨髓间充质干细胞(BMSCs)在Ti/PPy/rhBMP-2表面增殖、分化能力的检测,评价Ti/PPy/rhBMP-2对骨髓间充质干细胞增殖、分化的影响。

    The effects of Ti / PPy / rhBMP-2 on the proliferation and differentiation of BMSCs were evaluated .

  10. 根据细胞形态特征及诱导分化能力,证明我们分离的细胞即为MSCs。

    According to cell morphology and potential of differentiation , we determined the cells we isolated were MSCs . 3 .

  11. 目的:探讨1,25-(OH)2VitD3对小鼠牙囊细胞向成骨细胞(成牙骨质细胞)分化能力的影响。

    AIM : To explore the effect of 1,25 - ( OH ) _2Vit D_3 on cytodifferentiation of mouse dental follicle cells .

  12. 结论:1、经鉴定,本实验分离培养的BMSCs具有多向分化能力,并表达间充质干细胞特异性表面标记物。

    The isolated BMSCs have the multi-differentiation potentials and express the specific markers of mesenchymal stem cells . 2 .

  13. 结论:雌激素能增强大鼠ADSCs体外诱导成脂分化能力,其体外诱导成脂分化能力随着增龄性变化下降。

    Rat ADSCs in vitro proliferation and induced adipogenic differentiation capacity decline with age-related changes .

  14. 结论CML患者骨髓中存在具有多向分化能力的MSCs,其具有在体外支持造血的功能。

    Conclusion There are MSCs with multidirectional differentiation potential in CML bone mar - row and they possess the ability of hematopoiesis support .

  15. 计算成肌细胞肌管形成率(RMF)评价其分化能力;

    The differentiation was tested by the rate of myotube formation ( RMF );

  16. 结果:培养的MSC呈现出CD90、CD105强阳性,具有成骨、成脂肪等多向分化能力;

    Results Cultured MSCs had the ability of multipotent differentiation and highly expressed CD105 and CD90 ;

  17. 目的探讨生长因子IGF-I和bFGF对体外培养人类牙乳头间充质细胞增殖和分化能力的影响。

    Objective To research the effect of IGF-I and bFGF on proliferation and differentiation ability of human dental papilla mesenchymal cell ( hDPMCs ) .

  18. 目的:间充质干细胞(MesenchymalStemcells,MSC)是近年发现的来源于中胚层的一类非造血成体干细胞,具有干细胞的共性:高度自我更新和多向分化能力。

    Aim Mesenchymal stem cells discovered recently is a kind of adult stemcells derived from mesoblast . It has the commonness of stem cells that is capable of self-renewal and differentiating into many cell lineages .

  19. 扫描电镜(SEM)观察细胞生长情况,生物化学检测和实时定量PCR检测DPSCs的分化能力。

    At different time points during cells cultured , scanning electronic microscopy ( SEM ), biochemical tests and real-time PCR to observe differentiation potential of DPSCs . 3 .

  20. ADSCs体外扩增和自我更新能力很强,传代培养易于获得大量有分化能力的细胞。

    ADSCs have strong ability to self-renewal and mass culture accessible to a large number of cell differentiation in vitro .

  21. 诱导时间不同,愈伤组织的分化能力不同,本研究表明,2,4-D诱导体细胞胚的最佳时间为21d。

    Induction days had an effect on the re-differentiation of callus , study showed that the best induction days was 21d .

  22. 用第三代MSCs进行骨向诱导,以观察两种方法所获MSCs是否有相似的骨向分化能力。

    The MSCs were also undergone osteogenic differentiation by addition of osteogenic supplements to verify whether the MSCs obtained by the two methods had similar osteogenic differentiation potential or not .

  23. 对所分离的EG细胞经形态观察、AKP染色、体外分化能力检测,证实其符合小鼠EG细胞的一系列特征。

    When isolated EG cells were examined by observing morphology , AKP stain and in vitro differentiation capacity , it have a series of characters of mice EG cells .

  24. HSC衰老是指细胞生长停滞,不可逆的停留在G1期,自我更新和多向分化能力降低,细胞数量减少,应激性凋亡升高。

    HSC senescence is cell growth arrest , irreversible remain in G1 phase , self-renewal and differentiation capacity reduced , the number of cells decreased and apoptosis increased .

  25. 统计学分析比较第2、4、7代(P2、P4、P7)BMSCs诱导后增殖能力及向软骨细胞分化能力的变化。

    Statistical analysis of the proliferation and chondrogenic differentiation abilities of induced BMSCs was deployed among 2nd , 4th and 7th passages .

  26. MSCs具有容易分离培养、多向分化能力、免疫排斥反应小的特点,已经成为构建组织工程十分重要的种子细胞。

    MSCs , with the characteristics of easy separation , multiplex differentiation capacity and weak immune rejection , have already become a kind of very important seeded cells for tissue engineering construction .

  27. 结论:细胞核DNA含量和倍体及血清PSA的测定是反映前列腺癌细胞增殖分化能力的重要生物学指标,为正确诊断恶性肿瘤提供依据。

    Conclusion : Nucleus DNA content , its ploidy and serum PSA are the vital biological indicators of PC cell proliferation and the measurement of the three can provide valuable reference for the proper diagnosis of malignant tumor .

  28. 结论GFP转基因小鼠骨髓MSCs在体外诱导下具有多向分化能力,对GFP稳定表达无影响,可以作为研究MSCs多向分化潜能机制的一个有效示踪工具。

    Conclusion The limited cell strain of GFP-MSCs possesses multi-lineage potential , which can be used as an efficient tracking facility for studying the mechanism of multi-lineage potential on the MSCs .

  29. 为使愈伤组织保持旺盛的活力和分化能力,在继代培养中逐渐以NAA代替2,4-D。

    To keep the hearty vigor and differentiation ability of callus , and 2 , 4-D was gradually replaced by NAA , MS + 6-BA 0.5 mg .

  30. 结果显示,两种融合方式对细胞的融合率没有显著差异,但电融合的细胞植板效率和愈伤组织分化能力均显著高于PEG融合法。

    The results showed that no much difference existed in the fusion efficiency between the two methods , but higher cell plating frequency and a stronger plant differentiation ability of callus were observed in electrofusion .