乙酰胆碱受体
- 名acetylcholine receptor
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大鼠纹状体边缘区内烟碱型乙酰胆碱受体mRNA的表达
Expression of nicotinic acetylcholine receptor mRNA in the marginal region of rat striatum
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毒蝇碱型乙酰胆碱受体经Ras-ERK-1/2信号通路上调Bcl-2和磷酸化Bad表达
G-protein-coupled Muscarinic Acetylcholine Receptor Activation Up-regulates Bcl-2 and Phospho-Bad via Ras-ERK-1 / 2 Signaling Pathway
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重症肌无力B细胞免疫应答涉及乙酰胆碱受体的全部亚单位
The B Cell Repertoire in Myasthenia Gravis Includes All Four Acetylcholine Receptor Subunits
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大鼠神经肌肉接点N型乙酰胆碱受体密度测定的ELISA法
An ELISA for the determination of N-Ach receptor in nerve-muscle joint of rat
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氨基甲酸酯类药物和梭曼对N乙酰胆碱受体代谢的影响
The Effects of Carbamates and Soman on the Metabolism of Nicotinic Acetylcholine Receptors in Cultured Skeletal Muscle Cells
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G(12)亚型G蛋白对M3乙酰胆碱受体介导的磷脂酶D调控
Regulation of M_3 muscarinic acetylcholine receptor-mediated PLD stimulation by G_ ( 12 ) - type G proteins
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由于抗乙酰胆碱受体抗体的异质性,B淋巴细胞集合程度并不能反映临床症状的轻重。
The degree of B lymphocyte subgroup aggregation can not truly reflect clinical status because of the heterogenity of antibody against acetylcholine receptor .
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不同配体对m5乙酰胆碱受体-G蛋白亚单位G(11)融合蛋白表达和功能的影响
Effects of various muscarinic ligands on the expression and function of m_5 muscarinic acetylcholine receptor-G_ ( 11 ) fusion protein
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乙酰胆碱受体δ、γ亚基上LoopF高可靠性结构模型的构建
High Reliable Conformation of Loop F on δ / γ Subunits of Nicotinic Acetylcholine Receptor Constructed by Flexible Docking
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经GC治疗后,大多数患者抗乙酰胆碱受体抗体滴度较治疗前明显降低。
Anti - acetylcholine receptor ( AChRAb ) titers were markedly decreased after GC therapy .
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PCR扩增抗乙酰胆碱受体单克隆抗体重链可变区基因的反应条件
Amplification of the heavy chain variable region gene of a monoclonal antibody against acetylcholine receptor by polymerase chain reaction
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中枢烟碱乙酰胆碱受体与Alzheimer病的研究
Studies on the relationship between CNS nicotinic acetylcholine receptors and Alzheimer 's disease
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结论MG患者的自主神经功能障碍可能与乙酰胆碱受体抗体侵犯平滑肌和交感神经有关。
Conclusions It is related dysfunction of autonomic to the antibodies of acetylcholine receptor which involve on smooth muscle and sympathetic nerve in MG patients .
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重症肌无力中乙酰胆碱受体抗体是针对N型乙酰胆碱受体(nAchR)糖蛋白的多克隆抗体。
In myasthenia gravis acetylcholine receptors antibody is n-type acetylcholine receptors ( nAchR ) glycoprotein polyclonal antibody .
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用ELISA法对56例重症肌无力(MG)患者治疗前后的血清乙酰胆碱受体(AchR)抗体进行了检测。
Anti-acetylcholine receptor ( AchR ) antibodies in sera of patients with myasthenia gravis ( MG ) were detected with ELISA .
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抗乙酰胆碱受体单克隆抗体A7诱导实验性自身免疫性重症肌无力作用
The Effect of Anti-acetylcholine Receptor Monoclonal Antibody A7 in Experimental Autoimmune Myasthenia Gravis
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重症肌无力(MG)是由乙酰胆碱受体抗体介导的细胞免疫依赖性和补体参与的神经肌接头部位的自身免疫性疾病,免疫应答异常是其发病本质。
Myasthenia gravis ( MG ) is cell immune-dependent and complement-participative autoimmune neuromuscular disease mediated by antibodies against the nicotinic acetylcholine receptor ( AChR ), Its essential pathogenesis is immune response dysfunction .
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乙酰胆碱受体(AChR)为其特异性抗原。
Acetylcholine receptor ( AChR ) is illness-specific antigen .
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ABC-ELISA测定重症肌无力患者血清抗乙酰胆碱受体抗体水平的研究
Detection of anti-AChR antibody in myasthenia gravis patients with ABC-ELISA
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目的观察吗啡依赖大鼠脊髓和脑干毒蕈碱型乙酰胆碱受体m1~5的表达。
AIM To observe mRNA expression of muscarinic acetylcholine receptors in spinal cord and brainstem in morphine dependent or withdrawal rats .
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目的:制备一种对重症肌无力致病性抗乙酰胆碱受体(AChR)抗体具有特异性吸附作用的免疫吸附剂。
Objective To prepare a desired specific immunoadsorbent for anti-AChR antibodies in myasthenia gravis patients .
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梭曼、沙林和VX对N-乙酰胆碱受体的作用
Effect of Soman on the Nicotinic Acetylcholine Receptor
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目的采用中药黄芪复方调节重症肌无力(Myastheniagravis,MG)患者血清乙酰胆碱受体抗体(acetylcholinereceptorantibody,AChRAb)水平,以探讨其治疗MG的可能作用机制。
Objective To observe the mechanism of Huangqi compound by regulating the acetylcholine receptor antibody ( AChRAb ) level in blood of myasthenia gravis ( MG ) patients .
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目的了解MG患者的乙酰胆碱受体(AChR)特异性细胞免疫应答。
Objective To explore the specific T cell mediated immunity against nicotinic acetylcholine receptor ( AChR ) in the patients with myasthenia gravis ( MG ) .
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结论用人工合成乙酰胆碱受体Tα125-147肽段免疫Lewis鼠可以成功制作EAMG动物模型。
Conclusion Immunization with synthesized peptide T α 125-147 of the AchR can induce animal models of EAMG in Lewis rats .
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目的研究乙酰胆碱受体抗体(AChRAb)IgG对大鼠隔斜角带核区胆碱能神经元的损害作用。
Objective To investigate the injuries of the septo-diagonal bands cholinergic neurons of rats caused by acetylcholine-receptor antibody ( AChRAb ) IgG .
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通过对3株抗乙酰胆碱受体(AChR)的α-银环蛇毒素(α-BT)结合区抗体的配位特异性测定和可变区基因序列分析,探讨重症肌无力(MG)的发病机制。
The sequence analysis and paratope mapping of three antibodies against α - bungarotoxin (α - BT ) binding sites on acetylcholine receptor ( AChR ) were studied .
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目的:研究脊髓横断后在骨骼肌神经肌肉接头处降钙素基因相关肽(CGRP)的变化及其mRNA在脊髓的改变,以明确CGRP对乙酰胆碱受体的调控作用。
SUMMARY Objective : To observe the changes of calcitonin gene related peptide ( CGRP ) in skeletal muscle and CGRP mRNA in spinal cord after upper motoneuron injury in rats .
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应用ABC-ELISA法分析43例重症肌无力(MG)病人血清中IgG-乙酰胆碱受体和突触前膜受体抗体亚型。
The subclass analysis of IgG-AchR and presynaptic membrane receptor ( PsmR ) antibodies in sera of 43 patients with myasthenia gravis was done by means of ABC-ELISA studies .
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目的:分析鸡乙酰胆碱受体(acetylcholinereceptors,AChR)γ亚基基因与不同发育阶段鸡骨骼肌核因子的相互作用。
Objective : To analyze the interactions between AChR γ subunit gene and nuclear factors present in developing chicken skeletal muscle .