trx
- 网络悬挂训练;硫氧还蛋白;蛋白;收发信机
![trx](../cache/434590.jpg)
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Trx has various biological functions in keeping stable redox status of cells .
硫氧还蛋白具有多种生物学功能,对维持体内稳定的氧化还原状态具有重要的作用。
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Sequence analysis verified that the sequence of the cloned cDNA is identical to that of rat TRX cDNA in Genbank .
序列分析表明,克隆所得序列与GenBank中大鼠硫氧还蛋白cDNA序列完全一致。
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These studies have shown that : TRX can suppress tumor cell apoptosis .
研究表明:TRX可以抑制肿瘤细胞凋亡。
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Trx plays crucial roles in regulating cell growth , apoptosis and gene transcription .
Trx具有调节细胞生长、抑制凋亡、调节基因转录等功能。
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CONCLUSION : TRX protein plays an important role in the defense response of myocardium against oxidative stress .
结论:TRX蛋白在心肌的氧化应激防御反应中起重要作用。
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Construction of recombinant adenovirus vector with TRX gene by Tet-Off induction
Tet-Off诱导的硫氧还蛋白基因重组腺病毒载体的构建
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Thioredoxin ( TRX ) is a widely distributed redox protein .
硫氧还蛋白(Thioredoxin,TRX)是一个分布广泛的氧化还原蛋白。
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Thioredoxin ( Trx ) is a small and conservative protein .
硫氧还蛋白Thioredoxin(Trx)是一类高度保守的低分子量蛋白质。
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Thioredoxin ( Trx ) is a kind of small molecule protein which is expressed in various organisms .
硫氧还蛋白(Trx)是一种广泛表达于多种生物的小分子蛋白质。
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Trx has many biological functions , such as antioxidation , resistance to apoptosis , growth factors and regulation of transcription factor activity .
Trx具有多种生物学功能,如抗氧化、抗凋亡、生长因子及调节转录因子活性等。
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Thioredoxin binding protein-2 ( TBP-2 ) is one kind of negative regulator of Trx .
硫氧还蛋白结合蛋白2(TBP-2)则是一种Trx的负调节蛋白。
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Morphine increased expression of Trx / CyclinDl / Cdk5 , and also decreased the number of apoptotic cells .
吗啡诱导Trx/CyclinDl/Cdk5的表达,减少了MPP+导致神经元凋亡。
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Trx system can dethiolate protein disulfides and thus is an extremely important regulator for redox homeostasis in the cells .
硫氧还蛋白系统能使蛋白质二硫化物脱硫醇,是细胞内氧化还原稳态的重要调节子。
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HPO could interact with TRX in vitro and in vivo , which is the critical cytokine in redox regulation .
体、内外实验结果表明,HPO分子和作为氧化还原开关的TRX分子在细胞内外存在直接的相互作用。
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Trx protects neuron from ER stress-mediated cytotoxicity induced by MPTP , and the molecular mechanism is still unclear .
硫氧还蛋白具有保护多巴胺能神经元免受MPTP所致内质网应激损伤,然而这一作用的分子机理还不十分清楚。
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Compared with air group , Trx mRNA expression in hyperoxia group markedly increased , peaking at d10 ( P < 0.05,0.01 ) .
结果高氧组肺发育明显受阻,与空气组比较,高氧暴露后TrxmRNA表达显著增强,且于d10时达高峰(P<0.05,0.01)。
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GGA , an inducer of Trx , inhibited the ER stress induced by MPP + in vitro .
在细胞水平,硫氧还蛋白诱导物GGA可以缓解MPP+引起的内质网应激,从而抑制细胞凋亡。
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Lines with low trx mRNA showed stronger resistance to pre-harvest sprouting during the period from 30 days after anthesis to 10 days after maturity .
其中6个株系在开花后30d至成熟后10d表现出明显的抗穗发芽特性。
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These results suggest that Trx overexpression by GGA inhibited ER stress by MPP + and reduced the apoptosis induced by MPP + .
这些结果说明GGA诱导的硫氧还蛋白高表达可以抑制内质网应激,从而,降低MPP+诱导的细胞凋亡。
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Objective To investigate the changes and potential role of the expression of thioredoxin ( Trx ) in lung of premature rats exposed to hyperoxia and its clinical significance .
目的研究高氧肺损伤早产鼠肺组织硫氧还蛋白(Trx)的表达及其临床意义。
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Although Trx has many biologic functions , its fundamental functions are regulating biologic redox equilibrium and preventing against oxidant injuries through its active site Cys-Gly-Pro-Cys .
虽然Trx具有多种生理功能,但其最基本的功能是通过其活性位点(Cys-Gly-Pro-Cys)调节体内氧化还原平衡及抗氧化损伤。
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Not only is this good news for you when taking your second or third go at a TRX class , but now that fifth floor walk-up is no problem .
这对于于你第二次或者第三次尝试“全身阻力训练”来说无疑是个好消息,而且一口气爬五层楼也不再是什么事儿了。
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Baicalin can increase the Trx level in protein level and transcriptional regulation both in vitro and in vivo , and also have protective effect on PD rats behavior change and peroxidation .
在整体动物实验中,黄芩苷对PD大鼠行为学变化和脑内过氧化反应有一定的保护作用。黄芩苷可以在蛋白水平和转录水平提高PD大鼠脑内的Trx浓度。
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It was also found that if mature HBD-2 was directly fused to the fusion partner TRX , fusion product could be expressed efficiently with high solubility even at 37C .
而且发现将HBD-2成熟肽与载体蛋白TRX直接融合也可以实现其在37℃的高可溶性表达。
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Suggesting decline of Trx in AD and the occurrence of apoptosis has important links and there may be through Cyto-C release and activation of Caspase-9 caused apoptosis .
提示AD中Trx的下降与细胞凋亡的发生之间有重要的联系,并且有可能是通过Cyto-C的释放和Caspase-9的激活而引起凋亡。
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By using the half rate technology , network capacity can be spread double without extra TRX or extra carrier frequency , which is an effective solution to resolve sudden traffic peak and the high traffic load .
目前,可通过采用半速率技术,在不需要额外增加载频或额外投入频率资源的情况下,能成倍提升网络容量,解决突发话务量和高话务量问题非常有效。
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All in all , the Trx h activity has been greatly enhanced and it has caused the higher activities of amylase , quick metabolism of carbon and strong seedlings-vigor in transgenic beer barley seeds .
总的来看,转基因大麦的Trxh活性得到了很大提高,而Trxh活性的变化又进一步提高了啤酒大麦籽粒中的淀粉酶活性,促进了碳代谢的进程,提高了籽粒发芽势。
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In addition , we compared the two immune protein sequence of amino acids with different animals , then we found C. sinensis MT and Trx was closer to the homologous protein of vertebrates in the evolutionary .
另外,通过两种免疫蛋白的氨基酸序列与其它动物相关序列比对后发现,青蛤的金属硫蛋白和硫氧还蛋白在进化上比较近于脊椎动物的同源蛋白质。
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In vivo , PTS , an inducer of Trx , inhibited the inflammation-or / and mitochondria-mediated neuron apoptosis through up-regulation of Trx .
另一方面,在活体动物实验中,硫氧还蛋白诱导物PTS通过诱导硫氧还蛋白的表达,抑制了炎症反应以及线粒体损伤介导的神经元凋亡。
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Whether there is another way for FGF-2 , that is through inducing the expression of TRX in non-small cell lung cancer to achieve the purpose of inhibiting tumor cell apoptosis , having not been reported at home and abroad .
FGF-2是否存在另一途径即通过诱导非小细胞肺癌中TRX的表达来达到抑制肿瘤细胞凋亡的,目前国内外尚未见报道。