synuclein

Research Progress in Biological Characteristics of Synuclein and Its Correlation with Cancer

神经突触核蛋白的生物学特性及其与肿瘤关系的研究进展

α - Synuclein phosphorylation takes part in mouse dopaminergic neuron protection

α-突触核蛋白磷酸化参与小鼠多巴胺能神经元的保护作用

Construction of Transgenic Expression Vector of Wild Type and Mutant Human α - Synuclein

野生型及突变型α-synuclein转基因表达载体的构建

Collaborative analysis of α - synuclein gene promoter variability and Parkinson disease

α-synuclein基因启动子变异性和帕金森病的协同分析

The expressing proteins of α synuclein were confirmed by Western blot analysis .

表达蛋白经Western杂交证实为a-突触核蛋白。

N-terminal of α - Synuclein Involved in Regulation of Mitochondrial Function

α-突触核蛋白N-端结构域参与线粒体功能的调控

The Influence of α - Synuclein Overexpression on Mitochondrial Membrane Structure with Atomic Force Microscopy

原子力显微镜检测过表达α-突触核蛋白引起的线粒体结构变化

Inclusive criteria : ① relevant to the role of α - synuclein ;

纳入标准为：①与α-突触核蛋白的作用有关。

Recent advances in the pathogenesis of Parkinson disease : α - synuclein and oxidative stress

帕金森病发病机制研究进展：α-synuclein与氧化应激

Manganese alters α - synuclein expression in rat brain

锰对大鼠大脑α-突触核蛋白表达的影响

Study on exons 3 and 4 of α - synuclein gene in Chinese familial Parkinson disease patients

家族性帕金森病α-共核蛋白基因第3、4外显子的初步研究

α - Synuclein Promotes Neurite Outgrowth of Primarily Cultured Rat Brain Neurons

α-突触核蛋白促进大鼠原代培养神经元突起生长

Enhanced Oligomerization of α - Synuclein in Sera of Patients with Parkinson 's Disease

帕金森病患者血清对α-突触核蛋白寡聚体形成的促进作用

CONCLUSION : There is a complex interplay between α - synuclein and mitochondria .

结论：α-突触核蛋白与线粒体之间存在复杂的相互作用。

α - synuclein pathology does not predict extrapyramidal symptoms or dementia

α-共核蛋白异常不能预测锥体外系症状或痴呆

Up-regulation and aggregation of α - synuclein in mouse model of parkinsonism

帕金森病模型鼠黑质α-突触核蛋白表达升高并集聚

The expression levels of human α - synuclein in the brains of transgenic mice were analyzed by immunohistochemistry staining .

采用免疫组化鉴定人α-synuclein在小鼠脑组织中的表达情况。

Effect and Its Mechanism of α - Synuclein Knockdown on Dopaminergic Neurons in Parkinson 's Disease in Vitro Model

RNA干扰α-突触核蛋白对多巴胺能神经元的影响及其机制

Soluble expression and purification of human neuroprotein α - synuclein related to Parkinson 's disease and its antibody preparation

帕金森病相关蛋白α-共核蛋白的可溶性表达、纯化及抗体制备

Early studies had shown that α - synuclein was a toxic protein which played a key role in the process of neurodegeneration .

以往的研究证明α-突触核蛋白是一种在神经退行性病变中起关键作用的毒性蛋白。

Mechanism of curcumin 's protection of dopaminergic cells from rotenone-induced injury by inhibiting α - synuclein aggregation

姜黄素通过抑制α-突出核蛋白聚集保护鱼藤酮致多巴胺能细胞损伤的机制研究

The Effects of Exogenous Dopamine on Over-expression of α - Synuclein in Dopaminergic Neuron

外源多巴胺对α-Synuclein过表达多巴胺能神经元的影响

Expressions of α synuclein and tyrosine hydroxylase in nigral cells were investigated by immunohistochemistry .

应用免疫组化观察黑质细胞αsynuclein和酪氨酸羟化酶（TH）的表达；

However , the mutation and excessive expression of α - synuclein is through which molecular mechanism for the occurrence of PD still unclear .

但是，突变及过量表达的α-synuclein究竟是通过何种分子机制促进了PD的发生至今仍不清楚。

Some of nigral cells contained acidophilic Lewy body with intense immune response to α - synuclein ;

部分细胞胞质内出现αsynuclein免疫反应呈强阳性的Lewy小体；

Expression of Synaptophysin and α - Synuclein in the Brains of Parkinson Disease Rats with Trihexyphenidyl

安坦对帕金森病大鼠脑内突触素和α-突触核蛋白的影响

Research to Overexpression of Synuclein - γ in Rectal Adenocarcinomas Tissue and the Relationship between the Clinical Index of Tradition Chinese Medicine and Western Medicine

Synuclein-γ在直肠癌组织中表达及与直肠癌中西医临床指标关系的研究

Neurodegenerative Effect of α - Synuclein Fragment-NAC on Dopaminergic Neurons

α-synuclein片段NAC对多巴胺能神经元的神经变性作用

Objective To construct the transgenic expression vector of wild type and mutant human α - synuclein which can be specifically expressed in the central nervous system .

目的构建中枢神经系统特异表达的野生型及突变型-αsynuclein转基因表达载体。

The Neuroprotective Effects and Mechanism of Optimized α - Synuclein DNA Vaccine Immunize MPTP Inducing on Chronic Mouse Model of Parkinson 's Disease

优化人α-突触核蛋白核酸疫苗免疫MPTP帕金森病小鼠的神经保护作用及其机制研究