sphingolipids

Structure , Metabolic Pathway and Function of Sphingolipids in Plants

植物鞘脂的结构、代谢途径及其功能

Increasing investigation has shown that sphingolipids and their metabolites play an important role in plants .

最近的研究发现，鞘脂及其代谢产物在植物中也起着很重要的信号分子作用。

However , the biological function of sphingolipids in plants has been explored only recently and remains elusive .

鞘脂在植物中的研究最近几年才开始，植物鞘脂的功能还不十分清楚。

The results suggest that marine foods , including sea cucumbers , can be useful resources of the functional sphingolipids . 2 .

结果提示包括海参在内的海洋食品可以作为功能性鞘脂类的良好资源。

Backgrounds : Sphingolipids are the essential components of plasma membrane of eukaryotic cells and their metabolites usually work as important biological signaling molecules .

研究背景：鞘脂是真核细胞膜的主要成分，能代谢产生多种重要的信号分子。

Sphingolipids are ubiquitous , essential components of eukaryotic membranes and function as the dynamically signal factors between cells and the outer surroundings .

鞘磷脂类物质不仅是真核细胞膜的重要组成部分，也是细胞与外界环境之间重要的动态调节因子。

Ceramidase hydrolyze ceramide into fatty acid and chain base , which is an important part in metabolic pathway of sphingolipids .

神经酰胺通过神经酰胺酶水解生成脂肪酸和长链基团，它是以神经酰胺为中心的鞘脂代谢途径的重要组成部分。

These results indicated the existence of a subtle intertwined regulatory interaction between intracellular phosphoglycerol lipids and sphingolipids signaling pathways .

这些结果显示了细胞内甘油磷脂和鞘磷脂信号途径之间存在的精细调控作用。

Sphingolipidosis is a group of hereditary diseases characterised by the deficiency in enzymes responsible for catabolism of sphingolipids .

神经鞘脂病是一类神经鞘脂分解代谢障碍的遗传性疾病，酶学检测是确诊的一种主要手段。

Rafts rigidity ( is ) caused by the tight parking of cholesterol molecules against the straight single lipid ( sphingolipids ) hydrocarbon chain .

脂筏的刚性有赖于附着在鞘磷脂的直链周围的胆固醇分子。

Filipin Interferes with the Effects of N-Methyl-N ′ - nitro-N-nitrosoguanidine on Sphingolipids Metabolism in Human Amnion FL Cells

非律平菌素干扰甲基硝基亚硝基胍对FL细胞鞘脂代谢的影响

Myriocin induces apoptosis by depletion of cellular sphingolipids , inhibits proliferation of IL-2-dependent mouse cytotoxic cells and is a potent immunosuppressant .

嗜热菌杀酵母素通过耗尽细胞的鞘脂类诱导凋亡，抑制白介素2依赖性的小鼠毒性细胞的增殖，是一种有效的免疫抑制剂。

Single lipid ( sphingolipids ) rich raft ( s ) raised about the rest of the rafts ( lipids ) recuse ( recruits ) specified membrane proteins .

鞘磷脂组成的脂筏可以在其周围募集一些特定的膜蛋白。

GPI-anchored proteins often gather with sphingolipids ( including sphingomyelin and glycosphingolipid ) and cholesterol to form special plasma membrane microdomains ( GPI microdomain ) .

在细胞表面，GPI锚定蛋白常与鞘脂（包括鞘糖脂和鞘磷脂），胆固醇等聚集在一起形成具有特定结构和功能的质膜微区，称GPI微域（GPImicrodomain）。

Caveolae , a type of lipid rafts , is characterized by high levels of cholesterol , sphingolipids and proteins , and is identified by the presence of the protein caveolin .

小窝是脂筏的一种类型，由胆固醇、鞘脂及蛋白质组成，以小窝蛋白为标记蛋白。

There is now substantial evidence that sphingolipids and their metabolic products are involved in the regulation of cell growth , differentiation , survival , proliferation and programmed cell death via their participation as second messengers in specific signal-transduction pathways .

鞘脂及其衍生物在生物体内参与了极重要的细胞功能，它们可以作为第二信使调控细胞生长、分化、存活、增殖和程序性死亡等。

The research of sphingolipids in plants has been explored only in recent years , Far less is known about sphingolipids functions in plants . However , increasingly investigations indicate that sphingolipids and their derivants have important signalling roles in plants as well .

近几年才开始对植物中的鞘脂进行研究，目前植物鞘脂的功能还不十分清楚，然而最近的研究发现鞘脂及其代谢产物在植物中也起着很重要的信号作用。