sert

Median raphe nucleus did not show the decreased SERT labeling .

中缝正中核SERT标记强度未见显著降低。

SERT gene can be the candidate gene for therapy of IBS , which will have potential application prospects .

SERT可以作为治疗IBS的候选靶基因，具有潜在的临床应用前景。

Conclusion : MDMA can cause neurotoxicity to 5-HT system of central nervous system , and down-regulate the expression of SERT mRNA .

结论：MDMA对中枢5-HT系统有明显的神经毒性，导致SERTmRNA表达下调。

The neurotoxicity and SERT mRNA expression of MDMA

MDMA的神经毒性及SERTmRNA的表达

But the positive rate of SERT mRNA increased successively in D-IBS , A-IBS , control and C-IBS .

而SERTmRNA在D-IBS、A-IBS、对照组和C-IBS中的阳性表达率依次升高。

[ Objective ] To investigate the relationship between irritable bowel syndrome ( IBS ) of hepatic stagnation and spleen deficiency type and serotonin transporter ( SERT ) gene polymorphism .

[目的]探讨肝郁脾虚型肠易激综合征（IBS）与5-羟色胺转运体（SERT）基因多态性的关系。

In order to deal with the problems of skewed distribution and concept drifting , by integrating the current classification algorithms and Weighted Classifier Ensembles algorithm , a classification algorithm called SeRt with better adaptability is proposed .

针对两类数据流分布不平衡的问题和概念漂移现象，在结合当前经典的数据流分类算法和集成分类器算法的优点后，设计并实现了一种具有更好适应性的SeRt算法。

Results : Strongly labeling signals of SERT were mainly found in the rostral raphe nuclei of the rostral pons and midbrain in control group , while the signal was reduced in those nuclei of alcoholic group .

结果：健康组SERT免疫反应强标记信号在脑桥头侧和中脑主要集中分布在与中缝核群相同的区域。

Among the four regions studied of dorsal raphe nucleus , SERT labeling intensity significantly decreased by 38.9 % , 37.3 % , 16.5 % and 37.0 % of corresponding control respectively in ventral part , dorsal part , caudal part and interfascicular part .

在中缝背核的4个亚区中，中缝背核腹侧部、背侧部、尾侧部及束间部分别比健康组显著减少了38.9%、37.3%、16.5%和37.0%；

There are two important polymorphic sites in the SERT gene : variable number tandem repeats ( VNTRs ) in the second intron , and SERT gene-linked polymorphic region [ 5-HTTLPR ] , which might influence the transcription efficiency of SERT gene and the stability of the mRNA transcripted .

SERT基因存在2个多态性区：VNTRs和5-HTTLPR，由此产生的不同基因型可影响SERT基因的转录效率及其mRNA的稳定性，从而影响SERT的数量、亲和力以及5-HT重吸收。