post-transcriptional control

The methods to reverse cardiac remodeling was still deficiency in nowadays , people in the previous researches always focused on the post-translational regulation of neurohumor and signal transduction pathway in the pathogenesis of cardiac remodeling , while the research of the mechanisms of post-transcriptional control was not so much .

目前逆转心脏重构的手段仍较缺乏，之前的研究主要集中在心脏重构发病的神经体液和信号转导通路的翻译后调控，对于转录后调控的机制研究较少。

Hypoxia inducible factor 1 ( HIF-1 ), a nuclear protein with transcription activity , can make the body produce adaptive response to hypoxia / ischemia by binding to target gene , transcription and post-transcriptional control .

缺氧诱导因子-1（HIF-1）是一种具有转录活性的核蛋白，能与靶基因结合并通过转录和转录后调控，使机体对缺氧、缺血产生适应性反应。