p120

The expression and significance of p120 catenin in pancreatic carcinoma cell lines

连环蛋白p120在胰腺癌细胞株中的表达及其意义

P120 is the new member of catenin family .

P120（P120ctn）是连环素家族新发现的一员，它的生物学功能还没有被人们完全了解。

Expression of P120 Catenin in the Cell Lines and Tissues of Normal Liver and Hepatocellular Carcinoma

正常肝组织和肝细胞系、肝癌组织及细胞系中连环蛋白P120的表达

There might be a competitive relationship between p120 ctn and β - catenin .

p120ctn与β连环蛋白在一定条件下存在某种竞争关系。

Effect of Mangiferin on p120 ~ ( ctn ) phosphorylation and hepatocellular carcinoma cell biology

芒果甙对连环蛋白P120磷酸化及肝癌细胞生物学行为的影响

Expression of E-cadherin , β - catenin and p120 ~ ( ctn ) in so-called pulmonary sclerosing hemangioma

E-cadherin、β-catenin和p120~（ctn）在所谓肺硬化性血管瘤中的表达

The effect of several sulfureted fatty additives and phosphorus type additives P120 on the compatibility were investigated with four ball testing machine using the rapeseed oil as base oil .

以精制菜子油为基础油，在四球摩擦磨损实验机上考察了几种硫化脂肪添加剂和磷系添加剂P120的复配性。

Methods Reverse transcript polymerase chain reaction ( RT PCR ), immunofluorescence microscopy and immunohistochemistry methods were used to detect P120 catenin expression in the cells and tissues mentioned above .

方法采用RT-PCR、免疫荧光标记（激光共聚焦显微镜）和免疫组织化学分析，分别对正常肝细胞、肝癌细胞、正常肝组织和肝癌组织中P120ctn进行检测。

Results Immunohistochemistry results showed that the surface cuboidal cells of PSH were strongly positive on membrane for E-cadherin , β - catenin and p120 ctn , with cytoplasmic positive expression of β - catenin .

结果25例PSH的立方细胞中，三种上皮粘附分子E-cadherin、β-catenin和p120ctn均呈胞膜强阳性表达，β-catenin在胞膜强阳性表达的同时有胞质表达。

P120 ~ ctn , one member of catenin family , has the ability to control cadherin turnover , thereby regulating cadherin levels . It takes part in cell adhesion , mobility and is important in cell invasion and immigration .

p120~（ctn）为catenin家族成员之一，并能够调节钙粘蛋白的更新和代谢，在细胞的粘附、运动中起重要作用，与细胞迁移、侵袭等有重要关系。

Objective : To investigate the relationship of P120 ~ ctn phosphorylation and hepatocellular carcinoma cell malignant features , and to study the effects of a newly found flavonoid compound Mangiferin on P120 ~ ctn phosphorylation and cell biology .

目的：探讨P120ctn磷酸化与肝癌细胞恶性行为的关系，以及黄酮类化合物芒果甙对P120ctn磷酸化和肝癌细胞生物学行为的影响。