ntx

Study of Radiotherapy in Promoting Permeation and Absorption of NTX by Blood-brain Barrier

放射治疗对促进氨甲蝶呤血-脑屏障渗透吸收的探讨

Objective To investigate the effect of urine NTx in monitoring the effects of treatment osteoporosis with anti resorption drugs .

目的研究检测尿I型胶原交联氨基末端肽（NTx）监测抗骨吸收药物疗效的作用。

ICTP was much more worthy than NTX in diagnosis of breast cancer with bone metastasis .

成骨型生化指标在乳腺癌骨转移诊治中的价值不大。

Methods : The levels of urinary NTx and serum ICTP in 77 patients with malignant tumors were measured using ELISA .

方法：用ELISA方法测定77例恶性肿瘤患者尿NTx和血ICTP水平。

Effects of risedronate sodium on serum BGP and urine NTX / Cr in patients with postmenopausal osteoporosis

利塞膦酸钠对绝经后骨质疏松症患者血BGP及尿NTX/Cr的影响

Serum corticosterone level of NTx mice also lowered significantly and the concentration of met-enkephalin in hypothalamus even decreased to 51.8 % of the control group .

NTx小鼠的血清皮质酮水平明显降低。另发现NTx小鼠下丘脑甲硫脑啡肽（M-Enk）含量明显降低。

Results : NTx concentration and digree of pain existed a positive correlation ( P0.01 ); But no significant correlation with the number and bone metastasis position .

结果：血清NTx浓度和患者骨痛评分呈成正相关（P0.01）；但与患者骨转移涉及部位及转移灶数目没有明显相关性。

The results indicate that the ratios of Crosslaps / Cr and NTX / Cr are sensitive markers of bone resorption for monitoring secondary bone loss ;

结果表明：（1）尿Crosslaps／Cr、NTX／Cr、是继发性骨量丢失的敏感指标；

Conclusions Good control blood sugar can raise the bone density of 2 type diabetics , raises the level of BGP and IGF-1 , and reduces the level of NTX .

结论血糖的良好控制可提高2型糖尿病患者的骨密度，提高BGP、IGF-1水平，降低NTX水平。

SRE patients ( especially happen happened the pathologic fracture patient ) is obviously higher than none bone metastasis patients . 5 . Age is a impact factor of serum NTx concentration .

但发生SRE患者（特别是发生病理性骨折的患者）的NTx水平明显高于未发生SRE的骨转移患者；5.年龄和血清NTx浓度是肺癌患者骨转移的影响因素。

Diagnostic value of urinary NTX in patients with bone metastasis It is most efficient in clearing the peptide bonds on the C-terminal side of such amino acids tyrosine .

尿氨基末端肽在转移性骨肿瘤诊断中的意义它对裂开诸如酪氨酸这类氨基酸的羧基末端的侧肽链最为有效。

Result : The retention rate on NTX at the 6th month period was 33.4 % , whereas the previous abstinence rate of the same subjects was only 2.4 % .

结·果·：服用纳曲酮6个月的保持率为33.4%，与自身同期操守率（2.4%）比较具有显著性差异。

In the test of neurotransmitter releases in rat brain slices , both morphine withdrawal and NTX enhanced high potassium ( 30mM ) induced 5 HT release in slices of the area of the raphe nucleus .

吗啡戒断和NTX均可使高钾诱发的缝核区脑片5－HT释放增多。

This effect of EA was blocked by pretreated with opioid antagonist Naltrexone ( NTX , 15mg / kg , i. P. ) ; however the modulatory effects of EA on serum LZM , IgG were not affected by NTX .

这种增强作用可以被纳屈酮（NTX）所阻断，而对电针调节血清溶菌酶（LZM）、IgG含量的作用似不受NTX的影响。

Objective : To evaluate the benefits of using new bone metabolic markers such as urinary pyridinoline cross-linked N-telopeptides of Type I collagen ( NTx ) and serum pyridinoline cross-linked C-telopeptides of Type I collagen ( ICTP ) in the detection of bone metastasis in patients with malignant tumors .

目的：探讨溶骨性骨代谢生化指标尿Ⅰ型胶原交联氨基末端肽（NTx）、血Ⅰ型胶原交联羧基末端肽（ICTP）定量检测诊断恶性肿瘤骨转移的价值。