neurulation

Objective To investigate the roles and possible molecular mechanism of FGF8 in the neurulation and neural tube defect ( NTD ) .

目的探讨FGF8在神经胚形成和神经管缺陷（NTD）发生过程中的作用及其可能的分子调控机制。

The roof of the archenteron consists of cells invaginated over the dorsal lip . 3 . During neurulation the cells of the dorsal wall of the archenteron form the temporarily existed structures-the back fold and the subnotochord , which soon disappear .

原肠背壁细胞来源于背唇转入层，3.原肠背壁细胞在神经胚形成过程中，形成了短暂存在的原肠背褶和底索。

In order to study the molecular mechanisms of neurulation and NTD development , it 's important to investigate the differentially expressed genes during neural tube closing in mouse embryo .

研究小鼠神经管闭合过程中差异表达的基因有助于阐明正常神经系统发育和NTD发生的分子机理。

To investigate the spatio-temporal expression of hypoxia-inducible factor-1 ( HIF-1 ) during murine neurulation and explore the role of HIF-1 in the embryonic development of the nervous system .

为研究低氧诱导因子-1（HIF-1）在小鼠胚胎神经胚形成阶段的时空表达规律，探讨HIF-1在胚胎神经系统发生和发育过程中的作用。