muc1

Study on the Relationship between E-cadherin 、 MUC1 and Human Esophageal Carcinoma

E-cadherin、MUC1与食管癌预后关系的研究

Expression of Mucin gene ( MUC1 ) in variety classes breast cancer and clinical sense

MUC1基因在不同类型乳腺癌组织中的表达及其临床意义

MUC2 + / MUC1 + showed no significance in relation to all the clinical pathological parameters .

MUC2+/MUC1+型与各个临床病理参数均不具有相关性；

Our experiment has provided a reliable protocol for assaying genetic polymorphisms of goat milk MUC1 .

本研究为检测山羊乳MUC1遗传多态性提供了可靠的方法。

Objective To identify and characterize the mimic epitope of MUC1 from random phage display peptide library .

目的噬菌体随机多肽文库筛选及鉴定MUC1抗原的模拟表位。

There was MUC1 gene core protein expression in the glandular epithelial cells of cervix uteri and gallbladder .

宫颈组织中的腺上皮核周及胆囊内存在MUC1的表达。

Molecular Cloning of MUC1 / Y and Soluble Expression of Its Extra-cellular Fragment in E.coli

肿瘤MUC1/Y的克隆及其胞外段在大肠杆菌中的可溶性表达、纯化和鉴定

Effect of LAK cells mediated by MUC1 / CD_3 BsAb on MCF-7 cells in vitro

MUC1/CD3BsAb介导的LAK细胞对MCF-7细胞的体外杀伤作用

Expressions of MUC1 / Y gene in gastrointestinal cancer and induction of anti-tumor response by MUC1 / Y gene

MUC1/Y基因在胃肠道肿瘤中的表达及诱导抗肿瘤免疫

The objective of the study was to examine the genetic polymorphisms of milk MUC1 gene of goat breeds in Sichuan province .

本研究的目的是从基因水平上检测四川省地方山羊品种乳上皮黏蛋白MUC1的遗传多态性。

Objective To investigate MUC1 and MUC5AC expression in specimens of pancreas fine-needle aspiration and evaluate the diagnostic value .

目的检测胰腺细针穿刺标本中粘蛋白MUC1、MUC5AC的临床意义。

Soluble Expression of Peptide Containing MUC1 / Y-specific Epitope in Escherichia coli and Preparation of the Antibody

MUC1/Y特异表位肽在大肠杆菌中的可溶性表达及其抗体的制备

The vaccine is designed to induce an immune reaction to a molecule ( MUC1 ) on the outside of cancerous cells .

该疫苗被设计用于诱发癌细胞表面的MUC1分子产生一种免疫反应。

Objective To explore the expression of MUC1 , MUC2 and MUC5AC in large intestinal mucoid adenocarcinoma .

目的探讨黏蛋白MUC1、MUC2和MUC5AC在大肠黏液腺癌组织中的表达及意义。

MUC1 , a kind of polymorphism macromolecular glycoprotein , is known to be expressed on the surface of human endometrial epithelial cells .

MUC1是一种多态性的大分子糖蛋白，可在人子宫内膜上皮细胞表达。

Objective : To investigate the expression of MUC1 and MUC2 proteins and their significance in human bladder transitional cell carcinoma ( BTCC ) .

目的：探讨粘蛋白（MUC1）和MUC2蛋白在膀胱尿路上皮细胞癌中的表达及其与临床病理的相关性。

Conclusions Detection of MUC1 and MUC5AC expression in EUS-FNA specimens from pancreatic neoplasms could assist in the diagnosis of pancreatic cancer .

结论检测胰腺FNA标本中粘蛋白MUC1、MUC5AC的表达有助于提高对胰腺癌的诊断。

Conclusion Expression of MUC1 , MUC2 and MUC5AC can predict invasive and metastatic potential of large intestinal mucoid adenocarcinoma .

结论MUC1、MUC2和MUC5AC的表达可预示大肠黏液腺癌的浸润转移潜能。

Conclusion T739 mouse bladder cancer cell lines and tumor-bear model expressing human MUC1 were successfully established for the development of tumor vaccines targeting MUC1 .

结论建立稳定表达人MUC1T739小鼠膀胱癌细胞株和T739荷瘤小鼠模型，可用于肿瘤疫苗研究。

The aim of this study was to explore relationship between expression of mucin MUC1 and MUC2 in colorectal carcinoma and clinicopathological parameters and their clinical significance .

本研究的目的是探讨结肠直肠癌组织中粘蛋白MUC1和MUC2的表达与不同的临床病理参数间的关系及其临床意义。

Aim : To construct recombinant expression vector containing transcriptional regulation sequence of human breast cancer DF3 / MUC1 promoter and diphtheria toxin A-chain gene .

目的：构建含人乳癌DF3/MUC1启动子转录调控序列和白喉毒素A链（DTA）基因的重组表达载体。

Methods MUC1 core protein was detected in the normal gastrointestinal mucosa and tissues of intestinal metaplasia and gastric carcinoma with BC2 antibody by immunohistochemical SP method .

方法用BC2抗体和免疫组化SP法检测人正常胃肠道粘膜、肠化粘膜以及胃癌组织中MUC1基因核心肽的表达。

Research indicated that DF3 ( MUC1 ) tumor antigen expressions of human breast cancer in protein and RNA was almost 30 times to breast normal tissues and benign lesion .

研究显示人乳腺肿瘤中MUC1抗原在RNA和蛋白质水平表达几乎是乳腺正常组织和良性病变的三十倍【5】。

Then in the animal model , it could form tumors in the normal C57BL / 6 mice and immunohistological examination showed that this cell line could express MUC1 in vivo .

动物接种实验证实该细胞可在正常小鼠皮下成瘤，免疫组织化学检测可见该细胞系在C57BL/6小鼠皮下接种胰腺癌模型中可表达MUC1。

There are many anti-adhesion molecules and adhesion molecules playing a role in the implantation process . Mucin 1 ( Muc1 ) is one of the anti-adhesion molecules .

在植入过程中，有许多粘附分子和抗粘附分子发挥作用，粘蛋白1（Mucl）便是抗粘附分子之一。

Objective To explore the specific killing effect of diphtheria toxin A-chain ( DTA ) gene under control of the transcriptional regulation sequence of DF3 / MUC1 promoter .

目的探讨白喉毒素A链（DTA）基因在DF3/MUC1启动子调控下的杀伤作用。

Objective To investigate the expression of MUC1 in pancreatic intraepithelial neoplasia , pancreatic ductal adenocarcinoma tissue ( DAC ) and its clinical significance in the early diagnosis of DAC .

目的探讨MUC1在胰腺上皮内肿瘤、胰腺导管腺癌组织中的表达及其在胰腺癌早期诊断中的意义。

To elucidate the expression of MUC1 core peptide in the human normal glandular epithelial cells , the MUC1 core protein was detected with BC1 antibody by means of immunohistochemical LAB method .

揭示MUC1粘蛋白核心肽在人正常腺上皮中的表达模式。用BC1抗体和LAB免疫组织化学方法检测组织中的MUC1核粘蛋白的表达。

Results : The expression vector containing transcriptional regulation sequence of human breast cancer DF3 / MUC1 promoter and diphtheria toxin A-chain gene had been successfully constructed and identified by restriction endonuclease and sequencing .

结果：构建了含人乳癌DF3/MUC1启动子转录调控序列和DTA的表达载体，酶切和测序结果与预期完全相符。

Results : MUC1 / Y was only expressed in bladder carcinoma . Furthermore , the optical density mean value of MUC1 / Y was significantly lower in tumor group than in benign group and control group ( P < 0.001 ) .

结果：MUC1/Y仅在膀胱肿瘤中表达，且平均灰度均显著低于腺性膀胱炎组织和正常膀胱组织（P<0.001）。