lymphopenia

Establishment of a mouse lymphopenia model and its immune characteristics

小鼠淋巴细胞减少症模型的建立及其免疫学意义

Objective : To establish a mouse lymphopenia model via irradiation and to study its immune characteristics .

目的：以放射线处理建立小鼠淋巴细胞减少症模型并探讨其免疫学意义。

Conclusion Lymphopenia in the peripheral blood from the CRF patients shows immunodeficiency ;

结论CRF时外周血淋巴细胞减少表明CRF患者体内存在免疫缺陷；

Changed pattern of tumor immunity under lymphopenia setting and its significance in cancer biotherapy

淋巴细胞减少状态下的肿瘤免疫格局改变及其意义

Infants with T-cell lymphopenia may appear normal at birth and have no family history of immune disorders .

大多数婴儿T细胞淋巴瘤在出生时都变现正常，并且没有家族免疫系统疾病的病史从而较难早期鉴别。

Recipient lymphopenia state enhances the expansion and anti-leukemia effect of leukemia specific cytotoxic T lymphocytes

淋巴细胞缺乏状态对白血病特异性细胞毒性T淋巴细胞体内抗白血病效应的影响

In addition , some childhood vaccines given in early infancy may cause serious infection in children with T-cell lymphopenia .

并且，如果给予患有T细胞淋巴瘤而未被发现的患儿进行疫苗免疫，那么可能导致严重的感染。

Conclusion : Lymphopenia mouse model is successfully established and an enhanced immune protection can be induced under the lymphopenia status .

结论：以放射线处理成功建立淋巴细胞减少症模型，并具有增强免疫保护的效应。

New strategy of cancer immunotherapy : irradiation or chemotherapeutics-induced lymphopenia combined with immune reconstitution and tumor vaccine

放疗或化疗诱导淋巴细胞减少联合免疫重建和瘤苗免疫

Researchers say this is an important issue because early diagnosis and treatment of T-cell lymphopenia can dramatically improve the long-term health of the child .

研究者说只是一个非常重要的问题，因为T淋巴细胞的早期诊断和治疗可以极大提高患儿的健康状况。

Lymphopenia induced by cytotoxic chemotherapy , or pathologies such as HIV infection , can significantly weaken immune function ;

因为细胞毒性治疗造成淋巴球数目减少，或是HIV感染，会使免疫反应显著变弱；

Predictors of severity were household contact with other infected individuals , older age , lymphopenia , and liver dysfunction .

严重性的预测因子是家庭接触与其它被感染的个体、更老的年龄、淋巴球减少，和肝脏功能障碍。

Autoimmunity to CD4 T-cells may account for the persistence of the CD4 T-cell lymphopenia in such cases .

CD4细胞的自身免疫可导致持续性的淋巴细胞减少症。

Results The relative lymphopenia in 12 hours after onset of chest pain has the highest correlation with AMI , that is 61 3 % .

结果急性心肌梗死胸痛发生后12h内相对淋巴细胞减少的敏感性最高（613%）；

Purine nucleoside phosphorylase deficiency ( PNPdef ) presenting with lymphopenia and developmental delay : Successful correction with umbilical cord blood transplantation

以淋巴细胞减少症和发育缓迟为临床表现的嘌呤核苷磷酸化酶缺陷（PNPdef）1例：经脐带血移植得以成功治疗

There was significant difference in mean hospital time , SLEDAI , leukopenia / lymphopenia , 24h urine protein level , complement C3 level and one year death rate between infected SLE patients and control ones .

呼吸道及皮肤粘膜是本组SLE患者最常见感染部位；感染组较非感染组，平均住院日、SLEDAI、白细胞/淋巴细胞减少、尿蛋白水平、补体C3水平和1年死亡率差异显著；

Compared with non-critical SARS group , critical SARS group had lower minimum lymphocyte counts , larger range of lymphopenia and greater difference between neutrophilic granulocyte and lymphocyte counts ( P 0.05 ) .

与非重症组患者相比，重症组的最低淋巴细胞数目更低，最大淋巴细胞降幅更大，更多出现淋巴和中性粒细胞分离现象，两组相比具有显著性差异（P0.05）。

Examination of peripheral blood displays lymphopenia and obvious decrease in CD 4 + and CD 8 + counts . In addition , multi-foci of infiltration in the lungs are usually found by X-ray chest films .

检查有外周血淋巴细胞计数减少，CD4+和CD8+明显降低，肺内多发性浸润病灶。