immunotoxin

Purpose : To study formation of recombinant single chain immunotoxin .

目的：研究构建重组单链免疫毒素，对人体肿瘤进行导向治疗。

Vector construction and high level expression of single chain immunotoxin against ovarian carcinoma

抗卵巢癌单链免疫毒素的载体构建及高效表达

An experimental and clinical study of targeted therapy of human bladder carcinoma with immunotoxin

免疫毒素导向治疗膀胱癌的实验与临床研究

Specific Killing Effects of Immunotoxin BDI-1-PEA against Human Bladder Cancer Cells

抗膀胱癌免疫毒素BDI-1-PEA特异杀伤肿瘤细胞的研究

The development situation and application prospect of immunotoxin therapy in oral disease are reviewed in this paper .

本文主要综述了免疫毒素在口腔相关疾病生物治疗中应用的研究进展。

Preparation and characterization of anti-HIV-1 Recombinant single chain antibody and immunotoxin

抗HIV-1单链抗体、重组毒素的制备与功能测定

Construction , expression and targeting therapeutic of single-chain immunotoxin against hepatocellular carcinoma

抗肝癌单链免疫毒素的构建、表达及导向研究

Treatment and Prevention of Recurrence of Human Bladder Carcinoma with Intravesical Administration of Immunotoxin

抗膀胱癌免疫毒素导向治疗膀胱癌及预防膀胱癌复发

Construction of Anti carcinoma Immunotoxin Expressing Plasmid , Expression and its Killing Special to Carcinoma Cells

抗胃癌免疫毒素表达质粒的构建、表达及对肿瘤细胞的特异杀伤

The depletion of T cells in human cord blood by immunotoxin : efficacy and immune reconstitution

免疫毒素去除脐血T细胞的效率及对免疫功能重建的影响

Construction and identification of a humanized IL-2 immunotoxin

人源化IL-2免疫毒素的构建和鉴定

Objective To construct the immunotoxin BDI-1-PEA and study its cytotoxicity against human bladder carcinoma in vitro .

目的构建新型免疫毒素BDI-1-PEA，并进行抗人膀胱肿瘤活性的初步研究测定。

Methods for Determining the Cytotoxicity of Immunotoxin

免疫毒素的细胞毒性测定方法

The study on the autologous bone marrow transplantation purified in vitro with monoclonal antibody conjugated with immunotoxin

用单克隆抗体和免疫毒素体外净化骨髓行自体骨髓移植

Anti-T Cell Immunotoxin for GVHD Prophylaxis in Allogeneic Bone Marrow Transplantation

抗T免疫毒素用于异基因骨髓移植的实验研究及初步应用

Genetic recombination immunotoxin conjugated by the DTA and different vectors can kill the cells , which express special protein .

将DTA与单抗或其它能与肿瘤细胞特异结合的细胞因子等重组形成融合蛋白，能对一些表达特异蛋白的细胞产生杀伤作用。

The experimental study on an animal model of Alzheimer ′ s disease by intraventricular injection of the immunotoxin 192-IgG-saporin

免疫毒素192-IgG-saporin侧脑室注射建立阿尔茨海默病动物模型的实验研究

The preparation of immunotoxin and induce of immune unresponsiveness

免疫毒素的制备及特异性淋巴细胞无反应性的诱导

Replacement PE domain I a with antibody forms immunotoxin , which is extensively used in biotherapy of tumors .

用抗体取代PE结构域Ia形成免疫毒素（Immunotoxin），被用于肿瘤等的生物治疗。

Objective : We were to investigate the relationship between morphological changes in targeting of solid tumor with immunotoxin and underlying anti cancer mechanism .

目的：探讨免疫毒素对裸鼠移植人肺腺癌的抗癌机理与形态变化的关系。

Objective To study the selective toxicity of immunotoxin ( IT ) on T cells and to determine its effect on hematopoietic progenitor cells .

目的探讨抗T细胞免疫毒素（immunotoxin，IT）体外对脐血T细胞的清除效率及对造血干／祖细胞的影响。

Improvement of Selectivity and Cytotoxicity of IL-4 Immunotoxin on Lymphoma Through Site-directed Mutagenesis

定点突变提高IL-4免疫毒素对淋巴瘤的选择性和杀伤活性

Immunotoxin is a novel class of targeted agents in recent years , which is composed of toxin fragment and antibody or cytokine .

免疫毒素是近年来新兴的一种特异性靶向治疗药物，由毒素蛋白和载体两部分构成。

Conclusion Successful expression and purification of PEA are of significance for in-depth study of the pathogenic mechanism of Pseudomonas aeruginosa and preparing immunotoxin .

结论成功地对PEA全基因进行了可溶性表达和纯化，获得了稳定表达的工程菌，为深入研究PEA的致病机制和制备用于免疫导向治疗的重组毒素奠定了基础。

Doctors of Chinese medicine sector raised its etiology and pathogenesis is hot and humid Immunotoxin qi deficiency and blood stasis for their key .

目前中医界医家认为其病因病机是湿热疫毒，正虚血瘀为其关键。

Construction and Combined Cytotoxicity of Anti-CD3 and Anti-CD7 Monoclonal Antiboby-PAPs Immunotoxin

抗CD3、CD7单抗-PAPs免疫毒素的构建及其联合杀伤效应

The experimental study on the immunotoxin IL-10_ ( 23-57 - ) PE40

IL-10（23-57）-PE40免疫毒素的实验研究

AIM : To construct soluble expression vector of the recombinant immunotoxin against human bladder carcinoma and express and purify the immunotoxin with high biological activity .

目的：构建抗膀胱癌重组免疫毒素BDI1PE38/KDEL的可溶性表达载体，并表达、纯化具有抗肿瘤活性的可溶性蛋白。

At the same concentration , the anti T cell immunotoxin had no any influence on the proliferating rate of CFU-GM and BFU E.

该浓度的抗T免疫毒素对骨髓中造血干祖细胞的增殖没有明显影响。

Preparation and intracellular routing of immunotoxin rRTA : DS27

rRTA：DS27免疫毒素的制备及胞内运输研究