immune surveillance

AIM : To study the host immune surveillance functions by the neuropeptide methionine enkephalin ( met-enk ) .

目的：研究甲硫氨酸脑啡肽对机体免疫监督功能的影响。

BACKGROUND : Intercellular adhesion molecule 1 ( ICAM 1 ) plays an important role in immune surveillance , inflammatory reaction and phagocytose . There are few reports on how cell surface adhesion molecules express in the injured tissues of gout at home and aboard .

背景：细胞间粘附分子-1（ICAM-1）在免疫监督、炎症反应、吞噬等过程中起重要作用，但痛风的受损伤组织部位细胞表面粘附分子如何表达，国内外报道较少。

The function of antibody memory cells is immune surveillance . quick ;

利用所建立的抗体记忆矩阵实现对类似入侵抗原的快速应答，行使免疫监视识别功能。

Immune surveillance effect of TRAIL on the HBV infection

TRAIL对HBV感染的免疫监视效应研究

Advances of the Research on Mechanisms of Breast Cancer Escaping from Host Immune Surveillance

乳腺癌免疫逃逸机理的研究进展

The role mechanism of alpha fetoprotein in escaping immune surveillance of hepatoma cells

甲胎蛋白在肝癌细胞免疫逃避中的作用机制

Cancer cells evade immune surveillance is the important reasons of recurrence and metastasis of hepatocellular carcinoma .

肝癌细胞逃避免疫系统监视是肝细胞癌术后复发和转移的重要原因。

Tumor can escape from immune surveillance mechanisms of host self through a number of pathways or mechanisms .

肿瘤可以通过多条途径或机制逃逸宿主免疫监视。

Escaping mechanism of malignant nasopharyngeal carcinoma cell SUME from natural killer cell-mediated immune surveillance

人鼻咽癌细胞SUME逃逸NK细胞免疫杀伤机制的初步探讨

Methods The data of morbidity and immune surveillance of pertussis in 1991 - 2000 was analyzed by descriptive epidemiology .

方法利用描述性流行病学方法对1991～2000年百日咳发病、免疫和监测等资料进行分析。

Currently intensive researches have shown that NKG2D ligands expressed on leukemia cells are involved in leukemia immune surveillance .

近来研究发现白血病细胞表达多种NKG2D配体，参与白血病的免疫监视。

Immunity of liver cancer patients is compromised , mainly for T-cells inactivation and cancer cells evading of immune surveillance .

肝癌患者免疫功能低下，主要表现为T细胞活化障碍，癌细胞逃避机体免疫监视而产生免疫逃逸。

Tumor cells may escape from immune surveillance by highly expressing FasL and induce TIL apoptosis and perform infiltration and metastasis .

肿瘤细胞可能通过FasL的过度表达，逃避免疫监视，诱导Fas敏感的TIL凋亡，发生浸润和转移。

Human NKT cells in tumor immune surveillance , protection and inhibition of its potential to play a basic mechanism has not yet fully understood .

目前人类NKT细胞在肿瘤的免疫监视中，发挥保护和抑制作用的潜在基本机制还没有完全阐明。

As we understand more about the roles of antibody in immune surveillance , it will help to make immunotherapy of tumors a promising strategy .

抗体在免疫监视中的重要作用被逐渐认识，肿瘤免疫预防最终可能成为现实。

At present , the generation , development and metastasis of tumors were considered the result of tumor cell escape immune surveillance from T and NK cells .

目前认为恶性肿瘤的发生、生长和转移是其逃脱机体免疫监控的结果。

The result indicates that the phagocytosis suppression induced by the dusts instilled may facilitate cancer development owing to breakdown of immune surveillance .

结果表明：云锡等生产性粉尘对大鼠肺泡巨噬细胞的吞噬功能有抑制作用，从而使体内非特异免疫受到影响，破坏免疫监视系统，这可能是促使肺癌发生和发展的一个有利因素之一。

This result may imply that the escape of SARS virus from human immune surveillance may be the causality plays a very of SARS virus infection .

由此表明，SARS病毒引起人类发生严重疾病的原因可能与该病毒逃避机体免疫识别有关。

Conclusion : These data suggest that 5-Fu may enhance Fas expression in tumor cells and may increase the sensibility of them to Fas-mediated immune surveillance of the host .

结论：5-Fu可上调肿瘤细胞Fas表达水平，由此可能增加其对Fas介导的机体免疫监视作用的敏感性。

The allotropic expression strategy implies the potential apoptosis-inducing ability of perforin which may benefit immune surveillance and defense , and might also be adopted for therapeutic purpose .

异位表达的策略暗示了穿孔素潜在的凋亡诱导活性，而靶细胞的凋亡有助于机体的免疫监视和免疫防御，也提示穿孔素可以作为潜在的药物用于治疗。

Virus can exploit strategies to evade immune surveillance by CTL associated with NP , that indicates the importance of CTL response in controlling infection of virus .

与核衣壳蛋白有关的CTL免疫逃避的研究证实了CTL反应对于控制病毒感染的重要性。

Some human diseases closely link ERAD and certain viruses are able to exploit the host ERAD machinery to escape the immune surveillance and attacking .

ERAD与人类的某些疾病密切相关，有些病毒能巧妙利用ERAD逃遁宿主免疫监控和攻击。

Conclusion In cervical cancer loss of HLA class 1 expression play a decisive role in the escape from immune surveillance leading to a greater appear , infiltration , metastasis of tumor cell .

结论宫颈癌组织存在HLA-Ⅰ抗原部分缺失，形成免疫逃逸，导致肿瘤细胞的发生、发展、浸润和转移。

Conclusion HSPGs probably influence the expression of HLA - I on the surface of HCMV infected HELF . HSPGs indirectly regulate the HCMV immune surveillance evasion .

结论HSPGs可能参与影响HLA-I在HCMV感染的HELF细胞表面上的表达，对HCMV逃避宿主的免疫监视起间接调节作用。

Inhibition of apoptosis allows prolonged survival of tumor cells , and contribute to tumor cell to escape immune surveillance , such as radiotherapy and chemotherapy induced cell death , is an important mechanism of tumor development .

细胞凋亡受到抑制使得肿瘤细胞生存期延长，并有利于肿瘤细胞逃避机体的免疫监视及放化疗等引起的细胞死亡，是肿瘤发生发展的重要机制之一[4]。

CONCLUSION The expression of ICAM-1 and VCAM-1 in gastric adenocarcinoma was increased , but might not be sufficient for host immune surveillance of the tumor cells , on the contrary it might increase their mobility .

结论胃癌时ICAM-1和VCAM-1表达增高，但可能不足以产生针对肿瘤细胞的宿主免疫监视，反而有利于提高这些细胞的运动能力。

The epitope inducing neutralizing antibody in high variable region 1 ( HVR1 ) is the reason for escape of host immune surveillance , evolution of chronic infection , and also difficulty of producing wide spectrum vaccine .

由于诱导中和抗体的抗原表位恰好位于其包膜抗原E2蛋白的高变区1（HVR1），因而容易逃避机体的免疫监视，形成慢性感染，同时造成发展广谱预防性疫苗的困难。

Burnet developed the immunosurveillance concept in 1971 . Malignant cells obviously escape immune surveillance , which suggests that they possess the ability of evading any potentially lethal effector mechanisms operated by the immune system .

1971年Burnet首先提出免疫监视学说，认为免疫系统起了监视机体识别和破坏免疫性肿瘤细胞的作用。

Results Th1 / Th2 shift can be detected in the host after therapy of the tumor . Tumor cells escape from host immune surveillance by altering Th1 / Th2 , which could lead to tumor recurrence .

结果肿瘤治疗后体内出现Th1向Th2漂移，使肿瘤细胞逃避机体的免疫监视，导致肿瘤的复发。

Objective : To detect the expressions of Fas , FasL in human epithelial cancer ( OEC ) tissues and their tumor infiltrating lymphocytes ( TIL ) and explore the mechanism of neoplasmas escaping from immune surveillance .

检测Fas、FasL在上皮性卵巢癌及其肿瘤浸润淋巴细胞（TIL）中的表达，探讨Fas系统在卵巢癌免疫逃逸中的作用。