endostar

Each experimental group and negative control group , the expression differences had statistically significant . ( P0.01 ) Conclusion : Endostar inhibited the proliferation of Hela cell in a dose time-dependent manner .

各实验组与阴性对照组间及各实验组间相比，表达差异均有统计学意义（P0.01）。结论：重组人血管内皮抑制素对宫颈癌Hela细胞体外增殖有抑制作用，呈时间及剂量依赖性。

Objective : To reveal the synergistic antiangiogenic effects and mechanisms of novel recombinant human endostatin ( Endostar ) combined with cytotoxic drug cisplatin .

目的：揭示新型重组人内皮抑素（Endostar，恩度）与细胞毒药物顺铂联合使用的抗血管形成作用，探讨联合用药方式产生协同作用的分子机制。

Objective Recombinant human endostatin ( Endostar ) is the specificity of vascular endothelial growth factor , a large number of studies suggest that it could inhibit tumor growth through the inhibition of tumor angiogenesis .

背景及目的：人重组血管内皮抑制素（Endostatin，恩度）是特异性的血管内皮生长因子，大量研究提示其通过抑制肿瘤的新生血管起到抑制肿瘤生长的作用。

A novel recombinant human endostatin ( endostar ), combined with NP chemotherapy studied by scholars of our country , was approved by the State Food and Drug Administration of China in 2005 for the treatment of non-small - cell lung cancer .

我国学者自主创新研发的新型重组人血管内皮抑素（Endostar，恩度），2005年被我国国家食品药品监督管理局批准联合NP方案治疗非小细胞肺癌。

The aim of this study is to explore the angiogenesis effect of the elemene injection and combination of Recombinant Human Endostatin ( Endostar ) on liver cancer , especially to find whether the combination can cause synergism and to explore the mechanism of synergism . Methods : 1 .

本实验研究旨在积极探讨榄香烯注射液联合恩度对肝癌血管生成的影响，特别是联合应用是否具有协同增效作用，并进一步探讨其作用机制。