dxr

Conclusion Mouse-to-rat cardiac xenotransplantation can serve as an animal model of DXR .

结论小鼠→大鼠异种心脏移植可作为DXR研究动物模型。

Objective To establish a simple pig-to-monkey xenograft model to study delayed xenograft rejection ( DXR ) .

目的建立一个简便的研究延迟性排斥反应的猪&猴异种心脏移植模型。

Effects of Tetramethylpyrazine on the Accumulation of Doxorubicin in Human Drug Resistant Hepatocellular Carcinoma Cells Bel-7402 / DXR

川芎嗪对人肝癌耐药细胞Bel-7402/DXR多柔比星蓄积的影响

Objective : To elucidate the medicinal mechanism of Dingxin recipe ( DXR ) .

目的：探讨定心方抗心律失常的分子机制。

DXR is also characterized by recognition , infiltration and damage to grafts by various leukocyte subsets , including natural killer ( NK ) cells .

另外，多种炎症细胞如NK细胞对移植物的识别、浸润和损害也是DXR的重要特征。

Objective To observe induction of heat shock reaction by pretreatment of Doxorubicin ( DXR ) in long-term cold preservation-reperfusion injury of the rat liver .

目的观察阿霉素（DXR）预处理诱导大鼠肝脏热休克反应在肝脏长时间冷缺血-再灌注损伤中对肝细胞的保护作用。

Second , we investigated the injury of cultured rat cardiomyocytes by Hydrogen Peroxide ( H202 ) and the influence of DXR on it .

其次，利用心肌细胞ROS损伤模型和中药血清药理学方法，研究定心方药物血清对H2O2致培养心肌细胞损伤的影响。

Conclusion5F11-DXR can remarkably increase the cytotoxicity of DXR to the sensitive target cells and even effectively reverse the drug-resistant cell lines to DXR .

结论5F11-DXR对敏感靶细胞的杀伤作用较DXR明显增强，并可有效逆转耐药靶细胞对DXR的多药耐药性。

Methods The rats were administered intravenously by DXR at a dose of 1 mg / kg body weight in DXR group and by saline in control group .

方法供体大鼠术前按1mg/kg由外周静脉注射DXR（DXR组），对照组注射生理盐水。

For this purpose , fist , we researched the pathogeny mechanisms of MI / R injury and mechanisms of protective effect of DXR by the rat model of MIIR .

首先建立大鼠心肌缺血再灌注模型，从整体水平上探讨MI/R损伤的发病机制以及DXR的作用机制。

Conclusion : Through inhibiting the hypoxia caused 〔 Ca 2 + 〕 I and MMP elevation and MP lowering , DXR displays its action in protecting myocardial cells to prevent and treat arrhythmia .

结论：DXR能通过抑制缺氧引起的〔Ca2+〕i和MMP升高，及拮抗缺氧所致的MP降低，从而发挥保护心肌细胞，防治心律失常的作用。

AIM : To investigate the effect of sucking porcine liver extracts ( LE ) and doxorubicin ( DXR ) on BEL-7402 hepatoma cells in the renal capsulae of BALB / c nude mice .

目的：探讨乳猪肝提取物（LE）和阿霉素（doxorubicin，DXR）对裸小鼠肾包膜下移植BEL-7402肝癌细胞增殖、分化和凋亡的影响。

There are different reports in mechanism of DXR / AVR , most reports show that DXR is mainly initiated by cellular immune response , include T cell , CD4 ~ + cell , CD8 ~ + cell , NK cell and macrophages .

对于DXR的发病机制目前还有不同看法。多数研究报道认为DXR主要由细胞免疫所引起，参与DXR的细胞主要有T细胞、CD4+、CD8+、巨细胞。

Objective To investigate the role of inducible nitric oxide synthase ( iNOS ) expression and nitric oxide ( NO ) production in the delayed xenograft rejection ( DXR ) . Methods Heterotopic cardiac transplantation from mice to rats was used as a model of DXR .

目的利用小鼠至大鼠异位心脏移植模型，研究诱导性一氧化氮合酶（iNOS）和受体血清一氧化氮（NO）在延迟性异种移植排斥反应（DXR）中的作用。