dlbcl

Relapse and refractory on DLBCL patients is true a huge challenge for us .

难治复发是DLBCL患者治疗面临的一项巨大挑战。

Alterations of some genes and chromosomes can analyze DLBCL heterogeneity as well .

通过基因与染色体改变也可以建立判断弥漫大B细胞淋巴瘤异质性的模型。

Diffuse large B-cell lymphoma ( DLBCL ) is a highly heterogeneous disease .

弥漫大B细胞淋巴瘤是一种高度异质性疾病。

RESULTS : Six of the 60 DLBCL were bcl-2 / IgH positive by conventional PCR method .

结果：经常规法扩增bcl-2/IgH，有6/60例DLBCLbcl-2/IgH阳性；

Whether E2F1 can be used as a germinal center B cell DLBCL marker was also discussed .

同时对转录因子E2F1作为一种新的生发中心B细胞型DLBCL的判断指标的可行性进行探讨。

DLBCL cells developed well and passed stably . The shape of cell is round or ellipse . 2 .

结果：1.复苏的DLBCL细胞生长良好，传代稳定，细胞呈圆形。

The two molecules correlated somewhat with some clinicopathological features , but not with survival of DLBCL .

两者的表达对DLBCL的临床病理特征有一定影响，但与DLBCL患者的生存状况无明显相关。

CD10 / BCL-6 expression pattern may be helpful in identifying main variants of DLBCL .

CD10/bCL-6表达在识别变型中有重要意义。

Detection and Significance of Chromosome Abnormalities Where Bcl-2 and Bcl-6 Genes Locating in DLBCL

弥漫性大B细胞淋巴瘤bcl-2、bcl-6基因所在染色体区域异常的检测及意义

The DLBCL cells are reanimated , observe the proliferative status and morphological characteristic . 2 .

方法：1.DLBCL细胞的复苏与培养，观察细胞形态，了解生长情况和特性。

Analyze the effect of different dosage and different time on the cell cycle and cell apoptosis of DLBCL cell by FCM . Results : 1 .

应用流式细胞仪，分析不同剂量和照射后不同时间对DLBCL细胞的细胞周期和细胞凋亡影响。

Its incidence increased gradually in recent years . Diffuse Large B Cell Lymphoma ( DLBCL ) of NHL happened mostly in china .

近年来其发病率逐渐上升，我国NHL中以弥漫大B细胞淋巴瘤（DiffuselargeBcelllymphoma，DLBCL）最为多见。

Methods From 1997 to 2000 , 94 DLBCL patients were studied on the expression of survivin and caspase-3 detected by immunohistochemical stain .

方法收集1997年至2000年间初治弥漫大B细胞淋巴瘤94例，用免疫组化SP法检测其survivin、caspase-3表达情况。

The survival status of stage ⅰ E patient in both MALT lymphoma and extranodal DLBCL groups was better than patients of higher stages .

MALT淋巴瘤复发率低于结外DLBCL，而病人的5年生存率明显高于结外DLBCL。两种淋巴瘤的ⅠE期病人的存活情况较ⅠE期以上的病人好；

DLBCL was diagnosed through biopsy of cervical lymph node . It may be related to posttransplant lymphoproliferative disorder .

患者曾行肾移植术，颈部淋巴结活检后确诊为弥漫大B细胞淋巴瘤，考虑与移植后淋巴细胞增殖性疾病继发有关。

Objective : To investigate the diagnosis and mechanism of bone lymphoma ( diffuse large B-cell lymphoma , DLBCL ) with secondary hyperparathyroidism .

目的：探讨骨源性非霍奇金淋巴瘤（NHL）（弥漫型大B细胞性）伴继发性甲状旁腺机能亢进的诊断及机制。

OBJECTIVE To evaluate the therapeutic effects and side - effects of Rituximab on diffuse large B cell non - Hodgkin lymphoma ( DLBCL ) .

目的评价美罗华治疗弥漫型大B细胞性非何杰金氏淋巴瘤DLBCL的临床效果及不良反应。

DLBCL is one of most common entity in NHL , its morphology , immunophenotype , genetics and clinical presentation have obvious heterogeneity .

DLBCL是NHL中最常见的一种类型，在组织形态学、遗传学、免疫表型和临床特征上都具有明显异质性。

The expression rate of Bcl-2 and NF - κ B / p65 proteins in DLBCL have relation with clinical staging , effect and prognosis .

Bcl-2与NF-κB/p65蛋白在DLBCL中的表达与临床分期、疗效及预后有关。

The 5-year overall survival of gastric DLBCL accompanying MALT lymphomas was 38.5 % ( 5 / 13 ) .

后者的总体5年生存率为38.5%（5/13）。

Objective To evaluate the efficacy and toxicity of combination of Rituximab and CHOP regimen in diffuse large B-cell lymphoma ( DLBCL ) .

目的研究利妥昔单抗联合CHOP方案治疗弥漫大B细胞型淋巴瘤的疗效和不良反应。

Objective This study is to analyze the clinical characteristics of nodal , extranodal and Waldeyer 's ring diffuse large B-cell lymphoma ( DLBCL ) .

目的回顾性分析不同原发部位（韦氏环、结内与结外）弥漫性大B细胞淋巴瘤（DLBCL）的临床特征和预后。

Cases of diffuse large B-cell lymphoma ( DLBCL ) mainly expressed CD19 , CD20 , CD10 , and HLA-DR ;

4例弥漫大B细胞性淋巴瘤主要表达CD19、CD20、CD10和HLA-DR。

This review summarizes the morphological , immunophenotypic , cytogenetic and molecular genetic features of DLBCL relevant to the precise prognostic previsions .

作者综述DLBCL的形态学、免疫组化、分子生物学特点及与预后的关系。

In pediatric and young patient populations , the most common subtypes were LBL , DLBCL and Burkitt ′ s lymphoma .

青少年中最常见为LBL、DLBCL及Burkitt淋巴瘤。

By using the hemi-nested PCR for the second round amplification , 5 of DLBCL were positive , but all of the fresh tonsil tissues were negative .

进行第2次半巢式PCR时仅在DLBCL中发现5例阳性，新鲜扁桃体组织均阴性。

Objective To observe the mutation of 5 ′ noncoding region of bcl-6 gene in diffuse large B cell lymphoma ( DLBCL ) and its effect on lymphoma pathogenesis .

目的观察中国人弥漫性大B细胞淋巴瘤（DLBCL）中bcl6基因5′非编码区的突变情况，并探讨其作用。

DLBCL clinical manifestation show certain aggressive , although most DLBCL patients react to the traditional combination chemotherapy such as CHOP , but the really cure patients are less than half .

DLBCL（？）临床表现具有一定的侵袭性，尽管大多数DLBCL患者对传统的CHOP方案联合化疗敏感，但真正能治愈的患者不到一半。

Objective To investigate the characteristics of bcl-6 mutation , rearrangement and protein expression in Chinese diffuse large B cell lymphoma ( DLBCL ) populations , and to explore their clinical values .

目的：观察中国人弥漫大B细胞性淋巴瘤（DLBCL）中bcl-6基因突变、基因重排及蛋白表达的特征，探讨其存DLBCL发生中的作用及其临床应用价值。

The international prognostic index ( IPI ) is a standard approach to assess prognosis in DLBCL . However , the survival is different in patients with identical IPI score .

国际预后指数（IPI）对DLBCL患者的预后有很好的预测价值，但相同IPI分值患者治疗后生存期情况并不一致。