deiodinase

Effect of selenium on liver type I deiodinase in iodine-excess mice

硒对碘过量小鼠肝脏I型脱碘酶活性的影响

Preparation and Properties of Abzyme with Thyroxine Deiodinase

具有甲状腺素脱碘酶活性的抗体酶的制备及性质研究

5 ' - deiodinase activities decline by selenium deficiency in rat tissues

硒缺乏降低大鼠组织中5′-脱碘酶活性

A New Hypothesis about Iodine-induced Goiter and Hyperthyroidism : Deiodinase Activity Decrease Theory

高碘甲肿及碘致甲亢机制新假说：脱碘酶障碍学说

The study on the expression of type 2 iodothyronine deiodinase mRNA in hyperthyroid rat central nervous system

甲状腺功能亢进对大鼠中枢神经系统Ⅱ型脱碘酶mRNA表达的影响

The least dietary selenium requirements for normal expression of deiodinase and selenoprotein P and W in rats

大鼠脱碘酶、硒蛋白P和硒蛋白W正常表达所需的最低饲料硒水平

Effects of low iodine feeding on t_4 5 ' - deiodinase activity in brain tissue of newborn rats

低碘饲养对大鼠仔鼠脑组织T45′-脱碘酶活性的影响

Effect of nano-selenium on growth performance , activity of type ⅰ deiodinase and levels of thyroid hormones of weanling pigs

不同硒添加剂对仔猪生长肝脱碘酶Ⅰ活性和血清甲状腺激素水平的影响

The influence of nutritional selenium deficiency on the affinity labelling of type ⅰ and ⅱ 5 ′ - deiodinase

硒营养缺乏对亲和标记Ⅰ、Ⅱ型5′－脱碘酶的影响

Relationship of dietary selenium to liver iodothyronine 5 ′ deiodinase ( 5 ′ di ) in rats

膳食硒与大鼠肝脏5′-脱碘酶关系

Effect of dietary low calcium on hepatic type ⅰ iodothyronine 5 ' - deiodinase activity in the rats fed grains from Keshan disease endemic area

膳食低钙对饲克山病病区粮大鼠肝脏Ⅰ型T45′－脱碘酶活性的影响

Effect of Nano-Selenium on the Activities of Glutathione Peroxidase And Type-I Deiodinase in the Liver of Weanling Pigs

纳米硒对断奶仔猪肝脏谷胱甘肽过氧化物酶和脱碘酶I活性的影响

Effects of inborn iodine deficiency on T_3 T_4 nuclear T_3 receptor and T_45 ' - deiodinase activity in neonatal rat brain

先天性碘缺乏对新生大鼠脑内T3T4核T3受体与T45′-脱碘酶活性的影响

Type ⅱ deiodinase activity changes in rat brain tissue : Model group compared with the Control group is relatively lower , However , the difference was not statistically significant ( P0.05 ) .

大鼠脑组织中II型脱碘酶的活性的变化：Model组与Control组相比Ⅱ型脱碘酶的活性相对降低，但差别无统计学意义（P0.05）。

Adrenergic antagonist and agonist and antithyroid drugs on the activity of hepatic t_4-5 ' - deiodinase in rats

肾上腺素能阻滞剂和兴奋剂及抗甲状腺药对鼠肝T4-5′-脱碘酶活性的影响

After 2 , 4 , and 6 weeks , GSH-Px and 5 ' - deiodinase activities in selenium deficient rat tissues were significantly lower than that in control .

试验进行2、4、6周后，试验组大鼠组织中GSH-Px及5′-脱碘酶活性比对照组显著降低。

Modulation of type ⅰ iodothyronine 5 ' - deiodinase activity by selenium is probably due to selenium 's direct role as a cofactor of the enzyme ;

硒调节5′-脱碘酶活性可能因为硒是Ⅰ型脱碘酶的辅助因子；

Lower type ⅱ iodothyronine 5 ' - deiodinase activity might be caused indirectly by selenium deficiency through elevating local T4 level in tissues and circulating T4 level .

而Ⅱ型脱碘酶活性的变化则可能是缺硒导致组织局部T4水平升高的间接作用。

The main content of this dissertation is as follows : ⅰ . Clone and Sequencing of Gene Fragments of the Paralichthys olivaceus Deiodinase Iodothyronine Type I

牙鲆Ⅰ型甲腺原氨酸脱碘酶基因片段的克隆及序列分析

The activity of T_4 5 ' - deiodinase in rat liver and brain and serum T_4 , T_3 and rT_3 content were determined at 30 weeks of experiment .

测定了喂养30周大鼠肝脏、大脑组织T45'&脱碘酶活性以及血清T4、T3及rT3水平。

Conclusion The syndrome of nonthyroid disease after hemihepatectomy is contributed to the reduced serum 5 ' - deiodinase and serum albumin as well as the reaction of hyperinsulinemia .

结论肝切除术后出现非甲状腺疾病综合征，与5′&脱碘酶和血浆蛋白降低有关；

If Se is deficient , the deiodinase activity would be inhibited , the level of Circulation T4 will be elevated , and the concentration of T3 in peripheral tissues will be decreased .

缺硒时，该酶活性下降，使循环T4水平增高，外周组织T3水平下降。

The differences of thyroid weight , thyroidal peroxidase ( TPO ) activity , thyroidal iodine content , and renal ID ⅰ and cerebral type ⅱ iodothyronine deiodinase ( ID ⅱ) activities between two iodine groups were significant .

两碘组间甲状腺重量、甲状腺过氧化物酶（TPO）活力。甲状腺碘含量、肾脏IDⅠ及大脑Ⅱ型脱碘酶（IDⅡ）活力差异明显；

The levels of thyroid hormones were assayed by RIA , type ⅰ deiodinase ( IDI ) activities of liver and kidney were determined and the levels of mRNA of IDI in liver and kidney were detected by RT-PCR .

放射免疫法测定甲状腺激素水平，测定肝脏和肾脏组织Ⅰ型脱碘酶（IDI）活性，以RT-PCR测定IDImRNA水平。

In the liver and kindey of the rat , T_3 and T_4 both increased the T_45 ′ deiodinase activity , but T_3 proved to be a more potent enzyme inducer than T_4 ;

在肝肾中，T3，T4都增强T45′脱碘酶活性，T3作用更大一些；

The sensitivity of X. tropicalis to the contaminants is similar to that of X. laevis . Secondly , X. tropicalis embryos were exposed to a typical deiodinase inhibitor , iopanoic acid ( IOP ) .

其次，用典型的脱碘酶抑制剂碘番酸（IOP）对热带爪蟾胚胎分别进行24h暴露。

The chicks had higher ( P < 0.05 ) growth performance and GSH-Px at a concentration of 0.50 mg / kg as nano-Se than Na_2SeO_3 . ( iv ) Supplementation with Se increased the activity of type - ⅰ deiodinase in liver .

硒源添加浓度在0.50mg/kg时，纳米硒组肉鸡生长性能和GSH-Px活性显著高于亚硒酸钠组（P<0.05）。

Objective To investigate the effect of selenium supplementation on the brain development , the effects of selenium on activities of glutathione peroxidase ( GPx ) and deiodinase ( ID ⅱ), and the expression of growth-associated protein ( GAP-43 ) in chick embryo brain .

目的观察补硒对正常鸡胚脑谷胱甘肽过氧化物酶（GPx）、Ⅱ型脱碘酶（IDⅡ）活性和生长相关蛋白（GAP-43）表达的影响，探讨硒对正常动物脑发育的作用。