clonal expansion

We identified telomerase activity in follicle dermal stem cells and marrow MSCs and demonstrated that they were capable of clonal expansion .

检测两种干细胞端粒酶活性，结果证实它们具有克隆扩增的能力。

They arise when there is a clonal expansion of a mutated cell .

一个突变细胞如发生克隆性扩增，就引起这些大量突变。

The distribution and clonal expansion of TCR V β subfamily T cells in patients with lymphoma leukemia

淋巴瘤白血病患者TCRVβ亚家族T细胞的分布及其克隆性

Clonal expansion and specific cytotoxicity of autologous or allogeneic T cells induced by M_ 2a cells

AML-M（2a）细胞诱导自体及异体克隆性增殖T细胞及其特异性细胞毒性作用的研究

Molecular Characteristics of T-cell Receptor of Clonal Expansion of T Lymphocytes in Leukemia Patients after Haploidentical Bone Marrow Transplantation

白血病单倍型骨髓移植后T细胞克隆的T细胞受体分子特征

It is now believed that clonal expansion and tumor growth are the results of the deregulation of intrinsic proliferation and apoptosis .

细胞克隆性扩增及肿瘤生长是凋亡与增殖之间失去动态平衡的结果。

Multiple myeloma ( MM ) is a B-cell neoplasma characterized by clonal expansion of malignant plasma cells in the bone marrow .

多发性骨髓瘤（MM）是骨髓内异常浆细胞克隆性增殖性疾病。

CONCLUSION : A part of T cell acute lymphoblastic leukemia cells may arise from a clonal expansion of TCR V β subfamily T cell .

结论：部分T-ALL来自于TCRVβ亚家族克隆性增殖T细胞。

Conclusion : Restricted usage and clonal expansion of TCR V α subfamily T cells could be induced by CML associated antigens in vitro .

结论：CML相关抗原体外诱导脐血和正常人T细胞出现抗原相关的TCRVα优势利用和克隆性增殖。

Aim : To investigate the distribution and clonal expansion of TCR V β subfamily T cells in patients with B cell lymphoma leukemia ( LL ) .

目的：了解B细胞淋巴瘤白血病（LL）患者TCRVβ亚家族T细胞的分布及其克隆性。

Effect of vMIP - ⅱ on TCRV β Gene Expression and T Cell Clonal Expansion in SIV Infected Macaca Fascicularis

vMIP-Ⅱ对SIV感染的食蟹猴TCRVβ基因表达和T细胞增殖影响的探讨

Conclusion The PML-RAR α peptide could induce the clonal expansion T cells from cord blood in vitro , which may have specific cytotoxicity for PML-RAR α + cells .

结论PMLRARα多肽可在体外诱导脐血T细胞呈克隆性增殖，此优势增殖的克隆性T细胞可能具有特异性细胞毒作用。

Analysis of the Clonal Expansion of TCR V β Subfamily Genes and T Cell Clonality in AML-M_ ( 2a ) Using Genescan

基因扫描分析AML-M（2a）病人外周血的TCRVβ亚家族T细胞的克隆性增殖

Genescan analysis showed that clonal expansion of T cells could be found in 1-3 V β subfamilies from 2 cases with B NHL and 1 case with T NHL .

基因扫描发现2例BNHL和1例TNHL病人的1-3个Vβ亚家族T细胞呈克隆性增殖。

Objective To investigate the distribution and clonal expansion of TCR V β subfamily T cells in patients with cGVHD after unrelated donor bone marrow transplantation ( BMT ) .

目的了解非血缘关系骨髓移植后慢性移植物抗宿主病（cGVHD）患者的T细胞受体（TCR）VβT细胞的分布和克隆性。

Conclusions The skew distribution and clonal expansion of TCR V β subfamily T cells in patients with polycythemia vera might be a feature of the immune response for malignant cells .

结论PV患者外周血TCRVβ亚家族的优势表达和克隆性增殖可能是患者体内对抗恶性细胞的免疫反应特征。

The main characteristics of IEA are clonal expansion and multiple-parent random receptor editor operators . In addition , a modified hypermutation operator is introduced to improve the learning ability of individuals .

提出的α-随机克隆扩张和多受体随机编辑算子是该算法的主要特色，同时引入改进的超变异算子以加强个体的学习能力。

Objective To investigate the TCR V β gene repertoire , and to clonal expansion of T cells and T cell strains from peripheral blood of patients with T-cell acute lymphoblastic leukemia ( T-ALL ) .

目的了解T细胞急性淋巴细胞白血病（TALL）患者外周血中的T细胞及T细胞株的TCRVβ基因谱系及其克隆性增殖情况。

Conclusions T cells from cord blood may have the potential capability of proliferation in different TCR V β subfamily T cells , and the ability of restricted expression and clonal expansion , when T cells were induced by leukemia associated antigen .

结论脐血T细胞具备产生各TCRVβ亚家族T细胞的潜能，在白血病相关抗原诱导下，具有限制性和克隆性增殖的能力。

Conclusion The restricted usage and clonal expansion of TCR V β subfamily T cells from cord blood or patients with CML could be induced by CML cells , and the induced T cells have specific cytotoxicity against CML cells .

结论CML细胞可诱导脐血T细胞和自体T细胞TCRVβ优势利用和克隆性增殖，诱导后T细胞具有特异性杀伤CML细胞的作用。

Leukemia is a malignancy with the clonal expansion of hematopoietic progenitor cells , and the incidence rate of acute myelogenous leukemia ( AML ) is the first in all sorts of leukemia ( 1.62 / 100,000 ) .

白血病是一种累及造血干细胞的造血系统恶性肿瘤，而其中急性非淋巴细胞白血病在各种类型的白血病中发病率最高（1.62/10万）。化疗方法已使不少患者取得了疾病的缓解以至长期生存。

Currently , cyclosporin A ( CsA ) is believed to be able to block the production of T helper cell growth factor interleukin 2 ( IL 2 ), to affect interaction of T cells and B cells , and inhibit clonal T cell expansion .

目前认为环孢霉素A（CsA）可以阻碍辅助T细胞生长因子白介素2（IL2）的生成，影响T、B细胞的相互作用，抑制克隆性T细胞的扩增。