cellular aging

Research advances in cellular aging ( A review )

细胞衰老的研究进展（综述）

Mechanism of human cellular aging procedures .

这种变化很大程度上是人体各种细胞衰老过程机制所决定的。

Cell aging : early studies about cellular aging ;

细胞衰老：早期的细胞衰老研究；

Telomerase can lengthen telomere and delay cellular aging and its activity is regulated by many factors including some aging genes .

端粒酶能延长被缩短的端粒，延迟细胞的衰老，端粒酶的活性受到许多因素影响，其中包括与衰老有关的基因。

Therefore , whether a biomaterial strongly influences cellular aging process must be considered in the selection of a biomaterial for the biomedical application .

因此，在选择应用一个生物材料时需考虑该材料是否对细胞的衰老有很强的影响。

It seemed that the extracellular matrix ( ECM ) proteins adsorbed onto the EVAL surface might have a protective role in the cellular aging process .

表明吸附到EVAL表面的细胞外基质蛋白可延缓细胞的衰老进程。

Cellular aging is characterized by a decrease in telomere length , and this has been implicated as a mitotic clock that signals cells to stop division when telomeres reach a critically short length .

端粒随细胞分裂次数的增加而不断缩短，当缩短到临界长度时就会导致细胞衰老、死亡。

The telomere-telomerase hypothesis is the science of cellular aging and cancer . Telomeres are unique DNA-protein complexes at the terminals of chromosomes that play a critical role in protecting chromosomal integrity and in maintaining cellular replicative potential .

端粒是真核细胞内染色体末端的蛋白质-DNA结构，在保护染色体的完整性和维持细胞的复制能力方面起着重要作用，随着连续的细胞分裂，端粒逐步缩短，细胞老化死亡。

CONCLUSION : FLE can limitedly prolong the lifespan of the 2BS cells , and can induce the transcription of c-fos gene in aging 2BS cells , and provides theoretical basis for the genetic study of postponing cellular aging .

结论：枸杞子能有限的延长2BS细胞寿命，并对衰老2BS细胞c-fos基因转录有诱导作用，为延缓细胞衰老的基因学研究提供理论基础。

The best I can do is to say that Moderna could be the single most revolutionary drug company to be formed in at least the past decade ( or at least tied with Google-backed Calico , which wants to stop cellular aging ) .

我能做出的最好解释是，Moderna可能是过去至少十年中诞生的唯一一家最具革命性的制药公司，或至少是与谷歌支持的Calico平分秋色，后者旨在延缓细胞老化。

There are good arguments to see this process as a cellular model for aging . Human embryo lung fibroblasts ( HEL ) characteristic replicative senescence , due to the fact that HEL is a kind of diploid fibroblasts .

人胚肺成纤维细胞（HEL）属于二倍体成纤维细胞，具有复制性衰老的特性，因此选用HEL细胞作为研究对象，通过建立HEL细胞复制性衰老模型，来模拟正常细胞的衰老过程。

An international research group studied the effect of genetic variations on lifespan across the human genome , which could improve our understanding of the diseases and cellular pathways involved in aging .

国际研究小组研究了遗传变异对整个人类基因组寿命的影响，或能提高我们对老年疾病以及与年老相关的细胞通路的认知。

Objective To explore the change of the cellular immune function with aging through detecting the levels of CD3 ~ + , CD4 ~ + , CD8 ~ + T-lymphocytes and the expression of CD28 on CD4 ~ + 、 CD8 ~ + T cells in the peripheral blood .

目的通过对健康老年人与年轻人外周血CD3+、CD4+、CD8+T细胞及CD4+、CD8+T细胞CD28表达水平的比较性研究，探讨免疫衰老的细胞学机制。