biological half-life

Determination of the biological half-life of recombinant hirudin in rabbits

重组水蛭素在家兔体内生物半衰期的测定

Because of its poor solubility in water and short biological half-life in vivo , the current anti-cancer agent is not ideal .

但由于其水溶性差，吸收率低，体内生物半衰期短，目前有关制剂的临床抗癌疗效尚不理想。

The biological half-life of Cd is longer the that of Hg , Pb , As .

通过比较经济贝类对重金属的生物富集动力学特性的研究看出排出重金属Cd的生物学半衰期要长于重金属Hg、Pb、As。

However , the short biological half-life , the quick forming toleration , and the obviously side effect and unsuitable utilization make the clinical application of NO limited .

然而，NO生物半衰期短（15～30s）、易产生耐受性、副作用明显且使用不便等而使其临床应用受限。

The Prognostic Value of Serum Alpha Fetoprotein s Biological Half-life in Tumor Recurrence after Liver Transplantation for Hepatocellular Carcinoma ; Levels of plasma total homocysteine in the patients with early severe on-set pre-eclampsia and the study of interventional therapy

肝癌肝移植术后血清AFP生物半衰期对肿瘤复发的预测价值早发型重度子痫前期与血浆同型半胱氨酸浓度相关性及相应治疗

But the difficulty with hesperidin is low bioavailability ( 25 % ) . Hesperetin needs frequent drug administration to keep the level of plasma concentraion , because of its short biological half-life period and fast elimination after oral administration , which limits their clinical application .

橙皮苷本身生物利用度较低（25%），而苷元橙皮素半衰期短，口服给药后消除快，需频繁给药来维持有效血药浓度，从而限制了它们的临床应用。