allosteric

The small molecule causing the conformational change is an allosteric effector .

引起结构变化的小分子叫做变构效应场。

A New Model on Regulation of Allosteric Enzyme Activity

别构酶活性调节的一种新模型

A fundamental goal in signal transduction study is to understand allosteric communication .

对变构通讯的理解是研究细胞信号转导的一个基本目标。

A Heterotropic Effect Model for Regulation of the Allosteric Enzyme Activity

别构酶活性调节的异位效应模型

These results indicated that lactate dehydrogenase 5 had the character of V system allosteric enzyme .

结果提示LDH5具有V系统别构酶性质。

Allosteric enzymes possess an allosteric site in addition to their ACTIVE SITE .

别构酶控制着别构部位和它的活性部位。

The study on allosteric cooperative kinetics of DCMP deaminase from human blood lymphocytes

人血液淋巴细胞脱氧胞嘧啶核苷酸脱氨酶的别构协同效应动力学研究

Among the regulation mechanisms of cellular function , allosteric regulation is the most direct , rapid and efficient way .

在众多细胞功能调节机制中，别构调节是最为直接，有效并且快速的调节方式。

Clinical observation of therapeutic effects of allosteric snake neurotoxin Sn 114 cases of motor neuron disease

变构蛇神经毒素治疗运动神经元病114例的临床观察

The Allosteric Effect of Bilirubin on Human Placenta Glutathione S-transferase

胆红素对人胎盘谷胱甘肽S-转移酶的别构效应

Many agents cause weathering . multivalent allosteric inhibition

许多作用力引起风化。多价变构象抑制作用

Proteins which have two separate but interacting kinding sites are called allosteric proteins .

这种具有两个不同位置而又相互作用的蛋白质叫做变构蛋白质。

Analysis and realization of the method for predicting physical pathways of allosteric communi - cation in a protein family

蛋白质中变构通讯结构基础的方法分析与实现

These results provide the evidences that intrinsic millisecond dynamic network provide a mechanism for the transmission of allosteric signals throughout a protein .

这些结果说明蛋白质内部的毫秒动力学网络同样提供了变构信号在蛋白质内部传递的途径。

These domains can propagate signals from ligand-binding site to distal regions of the structure through allosteric communication .

这种结构域可以通过变构效应把信号从配基结合的位点传递到结构上比较远的位点。

Snake muscle fructose 1,6-bisphosphatase & purification , properties and allosteric activation by k ~ + ions

蛇肌果糖1,6-二磷酸酯酶的提纯、性质及钾离子激活的别构动力学

Allosteric effects of hemoglobin ;

血红蛋白的变构效应；

THE APPLICATION OF KAPPA PRODUCT TO THE REACTION RATE EQUATION OF OLIGOMER ALLOSTERIC ENZYMES The Method of Fast Calculation of Square and Multiplication on Binary Number System

Kappa乘积法在寡聚体变构酶反应速度方程中的应用二进制乘方、乘积速算法

Allosteric site of snake muscle fructose 1,6-bisphosphatase

蛇肌果糖-1,6-二磷酸酯酶的别构部位

Allosteric communication network of coupling residues in GPCR class A rhodopsin like family A fundamental goal in signal transduction study is to understand allosteric communication .

视紫质样GPCR中偶联氨基酸的变构通讯网络对变构通讯的理解是研究细胞信号转导的一个基本目标。

Following allosteric activation by intracellular acidification , NHE exchanges extra - cellular sodium for intracellular hydrogen with stoichiometry of 1:1 .

细胞内酸化变构激活NHE，以1：1的比例将胞外的钠离子与胞内的氢离子进行交换。

Allosteric effects of 5,5 ' - dithio-bis - ( 2-nitrobenzoic acid ) and its related compounds on acetylcholinesterase

5,5′-联硫-2,2′-双硝基苯甲酸及其有关化合物对乙酰胆碱酯酶的别构效应

In the study , we present the AlloSteric Database ( ASD ) which is the first online database that contains 336 allosteric proteins and 8095 modulators .

有鉴于此，在本项研究中，我们建立了别构数据库（ASD）。这是第一个有关别构调节的网络数据库，共包含336个别构蛋白以及8095个别构调节分子的相关信息。

Located in certain mRNAs , they can directly bind relevant small metabolites but not protein factors , and subsequently allosteric rearrangements modulate associated mRNA activities .

它位于特定的mRNA区域，可以不依赖任何蛋白质因子而直接结合小分子代谢物，继而发生构象重排，影响该mRNA的活动。

Studies have shown that protease molecule with two non-active site binding groove ( allosteric site ), can be used to develop drug resistance against HIV , the new strategy .

但这是一个开始，佩里曼表示，这一研究结果为开发新型的抗艾滋病药物奠定了结构基础。

We compared the CPR kinetics in E.coli system , S.cerevisiae system and human liver microsome . The allosteric kinetics of CPR was discovered in yeast system .

对大肠杆菌、酵母体系和人肝微粒体中CPR动力学进行了研究，发现在酵母体系中CPR出现了别构动力学。

Afterwards , all allosteric modulators from ASD were analyzed in comparison with various compounds from different databases to unveil the structural and qualitative characteristics of allosteric modulators .

之后，我们对所有ASD数据库中的别构调节分子进行了分析，通过与其他来自不同数据库分子的对比，探求别构调节分子的结构和性质特征。

CONCLUSION : Tricyclopinate inhibits neuronal nAChR by interacting with the allosteric sites rather than the open ionic channels or acetylcholine recognition site of the receptor .

结论：三环哌酯抑制神经元烟碱受体的作用部位在变构位点而不是在离子通道或乙酰胆碱识别位点。

Cause 2,3-BPG acts as an allosteric model and combines with the hemoglobin equally in amount . Thus it plays a critical role in adjusting the affinity between O2 and hemoglobin .

因为2,3-BPG是血红蛋白的别构调节物，与血红蛋白等摩尔结合，因此是调节O2和血红蛋白亲和力的重要因素。

AIM : To predict the allosteric communication network formed by a set of amino acids coupled with Leu-125 in G protein coupled receptor ( GPCR ) class A rhodopsin like family .

目的：预测视紫质样GPCR中由Leu125等氨基酸组成的变构通讯网络。