Terfenadine

Determination of terfenadine concentration in human plasma by LC-MS

人血浆中特非那定的LC-MS测定法

Effect of terfenadine on expiratory flow in asthmatic adults

特非那定对成人哮喘者呼气流速的作用

The Effect of Terfenadine on cAMP Concentration in Guinea Pig Plasma

特非那丁对豚鼠血浆cAMP相对浓度的影响

Inhibitory effect of terfenadine on the wheal reaction to skin test

特非那丁对皮肤试验风团反应的抑制作用

The purpose of this study was to objectively evaluate the efficacy of terfenadine .

本试验的目的是客观评价特非那丁的疗效。

Preparation of terfenadine oral suspension and its assay

特非那定口服混悬剂的制备及含量测定

AIM : To evaluate the therapeutic effect of terfenadine dispersible tablets for treating allergic diseases .

目的：临床验证特非那定分散片治疗过敏性疾病的疗效。

Objective : To find a ideal and unified mobile phase both of dissolution test and content determination of terfenadine tablets .

前言：目的：对特非那定片标准中溶出度检查与含量测定的流动相进行选择，统一为一个流动相。

A controlled trial of terfenadine in treating allergic and pruritic dermatoses in 146 patients

特非那丁治疗146例过敏性和瘙痒性皮肤病的对照试验

Multicenter , double-blind trial of terfenadine in treatment of urticaria and allergic rhinitis in 384 patients

特非那丁治疗荨麻疹和过敏性鼻炎的多中心双盲试验384例

The Effect of Terfenadine on the Down-regulation of β - adrenergic Receptors in the Lung of Guinea Pig

特非那丁对豚鼠肺组织β-受体向下调节影响的实验研究

A study on the effect of terfenadine , a histamine H_1 receptor antagonist , on normal and sensitized guinea-pig tracheal spirals in vitro

组胺H＿1受体拮抗剂特非那定对正常和致敏豚鼠气管螺旋条的作用

To investigate the effect of histamine H_1 receptor ( H_1R ) on pathogenesis in asthma , we studied the effect of terfenadine on guinea-pig spirals in vitro .

为了探讨组胺H1受体（H1R）在哮喘发病中的作用，我们研究了特非那定对豚鼠离体气管螺旋条的作用。

The results showed that the wheal reaction was inhibited by terfenadine , therefore , the end point dilution ( EPD ) changed from 10-5.6 to 10-3.9 ( P < 0.01 ) . There was no significant difference of wheal size and EPD in placebo group .

结果表明，特非那丁明显抑制了风团反应，平均终点稀释度从10~（-5.6）移至10~（-3.9）（P<0.01），而安慰剂组的风团大小及终点稀释度均无明显变化。

Varing degrees of amelioration of symptoms were seen in 86.7 % in the terfenadine group as compared to 74.8 % in the chlorpheniramine maleate group and 23.7 % in . the placebo group . Terfenadine was much more effective than placebo ( P < 0.01 ) .

特非那丁组86.7%患者症状有不同程度的改善，而扑尔敏组为74.8%，安慰剂组为23.7%，特非那丁的效果明显优于安慰剂（P<0.01）。