Riboswitch

Riboswitch : a gene expression regulatory element

核糖开关&一种基因表达调控元件

In bacteria , SAM is bound by the SAM riboswitch , which regulates genes involved in methionine or cysteine biosynthesis .

在细菌中，SAM是受了SAM核糖开关绑定的，该开关与蛋氨酸或半胱氨酸合成的基因相关。

In this thesis , we first perform a series of tests and comparison of different force fields and solvation models for the simulation of RNA . After that , we investigate a class of non-coding RNA with various regulation functions & riboswitch through molecular dynamic simulations .

本论文在对分子动力学模拟研究中力场参数和溶剂模型的选择做出比较评估的基础上，对一类具有多种调控功能的非编码RNA分子&核糖开关，进行了深入细致的模拟研究。

The interactions of a mutant form of guanine riboswitch GR ( C74U ) with series of amino modified purines , pyrimidines and imidazole derivatives are investigated . How the number and positions of amino groups affect the binding modes and binding affinity is included .

我们从理论上考察了突变的鸟嘌呤核糖开关GR（C74U）与氨基嘌呤、嘧啶和咪唑衍生物三种类似物之间的相互作用，以及氨基对结合方式和结合能力的影响。