Resistance to Drug

Conclusions The bacterial category and its resistance to drug in chronic patients changed a lot .

结论目前慢性肝病合并感染中，细菌种类和耐药性已发生了较大变化。

Mechanism of HIV ( h-uman immunodeficiency virus ) resistance to drug and preventive methods

人免疫缺陷病毒（HIV）抗药性的产生机理及控制方法

The resistance to anticancer drug is the main cause of the chemotherapy failure .

肿瘤细胞耐药性是导致化疗失败的主要原因。

An increase in resistance to the drug has been observed in several foci particularly in central Africa .

在若干疫源地，尤其是在非洲中部，已观察到对该药耐药性上升的情况。

HIV resistance to a drug may be detected in vitro by genotypicand phenotypic methods .

HIV的抗药性可在体外用基因型和表现型检测法来确认。

A complicating factor is that SP is becoming less effective in East Africa as people 's resistance to the drug grows .

一个让情况变得复杂的因素是，随着人们对于周效磺胺-乙胺嘧啶的耐药性增加，这种药物的效果在非洲东部正在减弱。

In the two latest cases , however , it appears that the virus rapidly developed resistance to the drug in patients as they were being treated for their infections .

在这两个最新的病例中，当患者接受治疗的时候，病毒在患者体内似乎迅速产生了对达菲的抗药性。

The bacterial biofilm has strongly resistance to the drug , which involves following mechanisms ( 1 ) to prolong the penetration of anti-bacteria agents through the bacterial biofilm ;

形成的生物膜具有极强的耐药性，其机制主要通过（1）延长抗菌剂渗透生物膜的时间；

However , they found no link between the use of enteric-coated aspirin and resistance to the drug ; past studies , they note , have had " conflicting " findings on this point .

但是，他们发现服用肠溶阿司匹林和阿司匹林抵抗之间没有关系，而以前有些研究却认为两者存在相关性。

A study in Malawi suggests that chloroquine is once again effective against malaria , over a decade after it was withdrawn from use in the country due to parasite resistance to the drug .

一项在非洲马拉维进行的研究表明，在氯喹因为疟疾耐药性而在该国停用十多年之后，这种药物再次对疟疾起效。

MDR refers to a cell resistance to toxic drug resistant cells , independent of the structure of many different mechanisms , or other produce cross-resistance to cytotoxic drugs , MDR genes by tumor cells caused by over-expression or amplification .

MDR是指抗某种细胞毒物药的耐药细胞，可对许多结构上无关或作用机制上不同的其他细胞毒药物产生交叉抗药性，可由肿瘤细胞的MDR基因过表达或扩增所引起。

We must have a good antiviral response to interferon and ribavirin , which significantly lowers the risk of resistance to the antiviral drug used in the combination .

对干扰素和利巴韦林治疗的反应性一定要好好，这样可以显著地降低联合用药时的耐药风险。

A patient with influenza A ( H1N1 ) appeared to show resistance to the antiviral drug , which has been used to prevent the virus spreading in communities .

一位甲型H1N1流感患者看上去表现出了对这种抗病毒药物的耐药性，该药已经被用于防止该病毒的社区传播。

An antibiotic used to combat multidrug-resistant tuberculosis in children could be leading to resistance to a similar drug in an unrelated bacterium that causes pneumococcal disease , say researchers .

科学家表示，一种用来治疗儿童耐多药结核病的抗生素可能导致患者产生对一种用于不相干病菌的药物的耐药性，这种病菌能引发肺炎链球菌疾病。

Resistance to the antiviral drug Tamiflu means that the threat of a pandemic , let alone the annual impact of illness and death from seasonal flu , remains considerable .

对抗病毒药物达菲（tamiflu）的耐药性意味着，病毒广泛流行的威胁仍然相当大，更不用说每年季节性流感带来的患病和死亡的影响。

The drug sensitivity test indicated that Shandong isolates are only sensitive to ampicillin , amikacin , cefotaxime , cefazolin , and have produced drug resistance to other routine drug at different degree . 2 , Detection of virulence-associated factors of streptococcus suis by multiplex PCR assay .

药敏试验结果显示，山东地区猪链球菌仅对氨苄西林、阿米卡星、头孢噻肟、头孢唑啉敏感，而对其他常规药物已产生了不同程度的耐药性。

There is no vaccine for the disease and there are signs of increasing resistance to the few effective drug treatments .

没有预防该病的疫苗，而有迹象显示该病对为数不多的有效药物的耐药性正在增加。

Distribution of the class ⅰ integron in Escherichia coli with multidrug resistance and its relationship to drug resistance

多重抗药大肠杆菌中Ⅰ型整合子的分布与抗药关系

Patients with advanced and recurrent-metastatic GIST should take imatinib continuously until they had resistance to imatinib and the drug could not control the tumor .

晚期和复发转移的GIST患者应该长期服用STI571，直到患者出现耐药而不能控制肿瘤。

The parasite responsible for the deadliest form of malaria is showing the first signs of resistance to artemisinin & the drug hailed as the biggest hope for eradicating the disease .

造成最致命类型的疟疾的疟原虫正在首次表现出对青蒿素的耐药性，这种药物被誉为根除疟疾的最大希望。

39 strains of salmonella typhimurium were tested for sensitivity to 12 kinds of antibiotics , All strains showed resistance to these antibiotics ( drug resistibility : 82.1-100 % ) except to gentamicin ( drug resistibility : 10.3 % ) .

39株鼠伤寒沙门氏菌，对12种抗菌药物进行敏感试验，除庆大霉素耐药率较低（10.3%）外，其他耐药率在82.1～100%。

Conclusions : MRP gene expression related to resistance of PEOC are major causes of resistance to MDR related drug .

结论：MRP基因表达与PEOC耐药有关，是抗MDR相关药物的重要原因之一。