Pyrimethamine

The effect of pyrimethamine on contact sensitivity and tolerance to DNFB in mice

乙胺嘧啶对二硝基氟苯所致小鼠接触超敏性和耐受性的影响

Orbital and vaginal hemorrhage was also noted in rats administered with chloroquine and pyrimethamine .

此外，孕鼠服氯喹与乙胺嘧啶后，尚有阴道与眼眶出血等中毒症状。

Existing drugs , such as pyrimethamine , are becoming increasingly ineffective as the parasite develops resistance to them .

现有药物正在变得越来越无效，因为疟疾寄生虫已经发展出对它们的抗性。

Analysis on results of antimalarial pyronaridine combined with sulfadoxine and pyrimethamine to falciparum malaria

抗疟药咯萘啶与磺胺多辛及乙胺嘧啶配伍治疗恶性疟结果的分析

Mice of the second generation in low dose spiramycin group and 1 mouse of the third generation in low dose pyrimethamine group were also found infected .

螺旋霉素低剂量组传第2代，20只小鼠中2只发病，乙胺嘧啶低剂量组传第3代，20只小鼠有1只发病。

Studies on the sensitivity of Plasmodium falciparum to pyronaridine / sulfadoxine / pyrimethamine in vitro

恶性疟原虫对咯萘啶/磺胺多辛/乙胺嘧啶敏感性体外测定方法的研究

Prospective randomized trial of trimethoprim / sulfamethoxazole versus pyrimethamine and sulfadiazine in the treatment of ocular toxoplasmosis

甲氧苄氨嘧啶/磺胺甲基异唑与乙胺嘧啶和磺胺嘧啶治疗弓形体性脉络膜视网膜炎的前瞻性随机化试验

The result of therapy of toxoplasmatic peritonitis administering Sulfadiazine and Pyrimethamine for 4-therapic courses was effective .

采用磺胺嘧啶和乙胺嘧啶治疗4个疗程，效果满意。

Comparative studies on the treatment of drug resistant falciparum malaria with single dose or two day regimens of pyronaridine / sulfadoxine pyrimethamine plus primaquine

咯萘啶与磺胺多辛-乙胺嘧啶单剂及两天疗法加伯氨喹治疗恶性疟的效果

The embryotoxicity of chloroquine and pyrimethamine in rats

氯喹与乙胺嘧啶对孕鼠和胚胎的毒性

[ Conclusion ] The in vitro method can be used to assess the sensitivity of P. falciparum to pyronaridine / sulfadoxine / pyrimethamine .

[结论]恶性疟原虫对咯萘啶/磺胺多辛/乙胺嘧啶的敏感性可用体外微量法进行测定。

Feulgen stain and microspectrophotometer were used for the study of the effect of pyrimethamine on the DNA amount of oocysts of Plasmodium yoelii yoelii .

本实验应用Feulgen组化染色研究乙胺嘧啶作用后约氏疟原虫卵囊内核酸含量的变化，并在显微分光光度计下进行DNA含量测定。

In tests against P. cynomolgi in rhesus monkeys , four compounds ( 1 , 8 , 20 , 25 ) were found to be less effective than primaquine and pyrimethamine in the same dosage level .

4个化合物（1,8,20,25，表2,3）进行了猴疟（P.cynomolgi）试验，效果不及伯喹和乙胺嘧啶。

The susceptibility of this chloroquine-resistant line to 7 antimalarials revealed more sensitive to pyrimethamine , sulfadoxine and primaquine , but exhibited some degree of cross resistance to the other 4 drugs , i. e.

对7种常用抗疟药敏感性测试的结果表明，该系除对乙胺嘧啶、周效磺胺和伯喹敏感外，对另外4种药物均显示出程度不等的交叉抗药性。

There were not specific medicine to toxoplasmosis , the drugs , such as pyrimethamine , acetyl spiramycin , et al , are used widely to treat toxoplasmosis , but the drugs only kill or depress tachyzoite , do not affect bradyzoites in the tissue cyst .

目前弓形虫病的治疗尚无特效药物，主要以乙胺嘧啶，乙酰螺旋霉素等药物为主，这些药物对速殖子有杀灭、抑制作用，而对包囊内的缓殖子几乎没有作用。