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IC50

  • 【医】【=50%inhibiting concentration】半抑制浓度
IC50IC50
  1. The IC50 of nearly 20 water extracts has been measured in the same system .

    并进一步测定了近20种水提物的半数抑制浓度。

  2. RESULTS : The IC50 of seven complexes in six human tumor cell lines is less than 10 μ g / ml.

    结果:七种稀土配合物对六株人实体瘤细胞株增殖的IC(50)值均低于10μg/ml;

  3. The IC50 and growth-inhibitory curves of cells were assayed by cell counting .

    用活细胞计数法求得各尺寸粒子的IC50,并绘制细胞生长抑制曲线。

  4. The smaller the IC50 was , the stronger the capacity of sample to scavenge active oxygen was ;

    IC50越小,表明样品清除活性氧能力越强;

  5. Cell viability decreased with raised concentrations and prolonged treatment of DMSO ; the IC50 was 3.2 % ;

    随着DMSO浓度的增加和处理时间的延长,细胞存活率明显下降,其IC50为3.2%;

  6. Results : The IC50 of VES in SGC-7901 cells was 101.45 μ g / ml.

    结果:VES对SGC-7901细胞的IC50值为101.45μg/ml;

  7. The concentration of ACE inhibitors needed to inhibit 50 % of ACE activity was defined as the IC50 value .

    将抑制50%的血管紧张素转换酶活性所需抑制剂浓度定义为IC50。

  8. Now six such compounds have been synthesized and their biological rape growing inhibiting activity ( IC50 ) has been determined .

    本研究报导合成的六个芳基脲类化合物,并利用油菜试法测定了它们抑制油菜胚根生长的生物活性;

  9. The IC50 of Taxol on A2780 / Taxol cell declined greatly ( P < 0.01 ) .

    紫杉醇对A2780/Taxol细胞的IC50显著降低(P<0.01);

  10. Method : The inhibitory concentration 50 % ( IC50 ) of VES in SGC-7901 cell apoptosis was observed by MTT .

    方法:采用噻唑蓝(MTT)法测定VES对SGC-7901细胞的半数抑制浓度(IC50值);

  11. MTT assay was used to detect die half-inhibition concentration ( IC50 ,) of aclarubicin on Hela cells .

    采用MTT(四甲基偶氮唑蓝)方法测定阿克拉霉素对Hela细胞的半数抑制率(IC(50))。

  12. This method was used to determination the antioxidant capacities of 18 kinds of flavonoids and anthraquinones , and their IC50 were computed .

    本法已用于十八种黄酮化合物及蒽醌类化合物的抗氧化能力测定,并计算出它们的IC50。

  13. In this experiment , 100 μ g / ml ( approximately 50 % IC50 ) used as the highest dose of nano-SiO2 .

    本试验中我们采用100μg/ml(约50%IC50)作为纳米SiO2的最高浓度。

  14. With the presence of capric acid , the IC50 values of caprylic and lauric acid deceased obviously .

    辛酸和月桂酸IC50值因为癸酸的存在而明显降低。

  15. Results Digitoxin or digoxin was able to kill K562 cells significantly with dose dependence . IC50 was 0.059,0.101 μ g / ml respectively .

    结果洋地黄毒甙、地高辛能显著杀伤K562细胞,并有剂量依赖性,IC50分别为0.059,0.101μg/ml;

  16. IC50 was calculated by LOGIT method and the effect of timeliness and dose of sucrose selenite was discussed on various kinds of cancer cells . 4 .

    并且用LOGIT法计算了蔗糖亚硒酸酯对不同癌细胞的半抑制浓度(IC50),同时探讨了其作用于癌细胞的时效性和量效性的关系。

  17. The result of the ACE repressive activities of oligopeptides from CGM indicated that IC50 was less than 1.33 % .

    采用体外检测法测定了玉米短肽的ACE抑制活性,结果表明:经冷冻干燥的玉米短肽的AEC抑制活性较高,其IC50小于1.33%。

  18. Methods : K562 was cultured in vitro and then studied by MTT to measure IC50 , so as to observe the cytotoxicity of quercetin ;

    方法:体外培养K562细胞,应用MTT比色试验测定IC50,观察槲皮素的细胞毒性作用;

  19. Results Treatment of A549 cells with EGCG resulted in significant dose-dependent and time-dependent inhibition . The estimated values IC50 was 46.54 μ g / ml.

    结果EGCG显著抑制A549肺癌细胞生长,具有时间依赖性和剂量依赖性,IC50是46.54μg/ml。

  20. Methods The cytotoxicity of different concentration of Aidi injection on nasopharyngeal carcinoma cell line CNE-2 was observed , and IC50 was calculated by Karber method .

    目的探讨艾迪注射液对鼻咽癌细胞系CNE-2的细胞毒性作用以及对放射敏感性的影响。

  21. The design method of heavy metal interaction experiments Basing on half growth inhibition concentration ( IC50 ) and common safety concentration , a new method of heavy metal interaction experiment design method was proposed .

    重金属交互作用试验设计的方法运用半抑制浓度和公共最大非抑制浓度两个参数,提出了一种重金属交互作用试验设计的方法。

  22. Compound 9 and compound 12 have strong free radical scavenging activity , the inhibition rates were 95.4 % , 90.1 % , the IC50 values were 0.01, 29.87 .

    经活性导向分离得到的14个化合物中,化合物9和化合物12具有很强的DPPH自由基活性,其抑制率分别为95.4%、90.1%,其IC5o值分别为0.01、29.87。

  23. The results showed that the melanin pigment inhibited lipid peroxidation in a dose dependent manner . The IC50 values were found to be 0.135mg/mL .

    结果表明,该天然黑色素能够显著抑制蛋黄的脂质过氧化,且具有明显的量效关系,其IC50为0.135mg/ml。

  24. The hydrolysate with hydrolysis degree of 15.96 % showed the highest inhibitory activity to ACE , and its inhibitory value of IC50 was 0.125mg/mL .

    水解度15.96%时所得水解物对ACE抑制作用最强,IC50为0.125mg/mL。

  25. RESULTS : A2780 cell growth was significantly inhibited by wogonin . The inhibiting effect showed concentration dependent and time dependent manners with IC50 of 85 μ g / ml.

    结果:汉黄芩素明显抑制A2780细胞增殖,抑制作用呈时间和浓度依赖性,48h的IC50为85μg/ml;

  26. Results The AA-induced sup - pression on sodium current was voltage-dependent and concentration-dependent , IC50 was 10.3 μ M.

    结果花生四烯酸对人心房肌钠电流的抑制作用表现为电压依赖性和浓度依赖性,IC50为10.3μM。

  27. Results In the study in vitro , the IC50 of TXT , which was obviously lower than that of the other 5 kinds of chemical drugs , was 15.8 ng .

    结果体外试验,TXT对ISOS-1的IC50为15.8ng/ml,比其他5种抗肿瘤药物明显低;

  28. Their antioxidant activity was evaluated by measuring the inhibition of lipid peroxidation in rat liver microsomes , with IC50 values of 9.0 ~ 14.0 μ g / ml.

    利用测定小鼠肝细胞微粒体脂质过氧化抑制作用的方法,检测了所得到的4种木脂素的抗氧化活性,其IC50值范围为9.0~14.0μg/ml。

  29. The IC50 for hydroxyl free radical scavenging of the extracts from fibre , leaf and flower were 11.85 , 7.21 and 11.22 mg / ml , respectively .

    须根、茎叶和花清除羟自由基(·OH)的IC50依次为11.85、7.21和11.22mg/ml;

  30. This ELISA method exhibited that the value of IC50 was 4.95ng / mL , and the range of linearity was 0-100ng / mL.

    本论文研制试剂盒的IC50为4.95ng/mL,线性范围为0~100ng/mL。