Harringtonine

Effect of Harringtonine and Homoharringtonine on Colony - forming Efficiency of Tumor Cells in vitro

三尖杉酯碱及高三尖杉酯碱对体外培养瘤细胞集落形成率的影响

Studies on the antineoplastic action and toxicity of partial synthetic harringtonine

半合成三尖杉酯碱的抗肿瘤作用及毒性研究

A Study on binding of harringtonine to bovine serum albumin

三尖杉酯碱与牛血清白蛋白相互作用的研究

These data showed that harringtonine may be a competitive inhibitor of DNA polymerase α .

上述结果初步表明三尖杉酯碱可能是酶的竞争性抑制剂。

Induction of Differentiation of Human Leukemia Cells by Harringtonine Combined With Cytarabine

三尖杉酯碱与阿糖胞苷联合诱导人白血病细胞分化的研究

Two-dimensional Polyacrylamide Gel Electrophoresis Analysis of Apoptosis in K562 Cells Induced by Harringtonine

双向凝胶电泳分析三尖杉酯碱诱导K562细胞凋亡

Determination of harringtonine in human plasma by HPLC

人血浆三尖杉酯碱高效液相色谱测定法

Ultrastructural Studies on Differentiation of Human Leukemic Cell Induced by Retinoic Acid and Harringtonine

维甲酸及三尖杉酯碱对人白血病细胞株诱导分化的超微结构

Effects of harringtonine on the apoptosis and proto-oncogenes expression in HL-60 cells

三尖杉酯碱对HL-60细胞凋亡及原癌基因表达的影响

The chronotoxicity of harringtonine on hemogram in rats Value Every Bit Of Time

三尖杉酯碱对大鼠血象的依时毒性

Study of the efficiency and stability of harringtonine encapsulation in whole phospholipid vesicle from human erythrocyte membrane

人红细胞膜脂三尖杉酯碱脂质体包裹率及稳定性的研究

Induction of apoptosis by harringtonine in HeLa cells

三尖杉酯碱诱导HeLa细胞凋亡的研究

Vitamine D3 and low-dose harringtonine in acute leukemia ( analysis of 22 cases )

维生素D3和小剂量三尖杉酯碱治疗急性白血病疗效观察（附22例分析）

The effects of harringtonine on nucleotide metabolism in Ehrlich ascites carcinoma cells have been studied .

本文用标记核苷参入艾氏腹水癌细胞各成分以研究三尖杉酯碱对有关的核苷酸代谢的影响。

Treatment of Acute Promyelocytic Leukemia with All - trans Retinoic Acid and Low - dosage Harringtonine

全反式维甲酸和小剂量三尖杉酯碱治疗急性早幼粒细胞白血病的临床观察

Conclusion : Therefore , choosing the optimum biological , chemical and physical conditions is an efficient way to increase the production of harringtonine .

诱导子能显著提高三尖杉酯类碱的含量。结论：择优筛选出有利于三尖杉酯类生物碱的生物、化学、物理因子，是提高悬浮细胞抗癌生物碱的有效途径。

Effects of harringtonine on peroxidation and dynamic microstructure of membrane lipids of myocardial sarcoplasmic reticulum in rat

三尖杉酯碱对大鼠心肌肌质网膜脂过氧化及膜脂分子运动的影响

Effects of harringtonine on the nuclear DNA structure in HL_ ( 60 ) cells and L_ ( 1210 ) cells

三尖杉酯碱对HL（60）和L（1210）细胞核DNA结构的影响

The aim of this study was to investigate the effect of bortezomib alone and in combination with harringtonine on apoptosis of HL-60 cells .

本研究探讨硼替佐米（bortezomib，Bor）单用或联合三尖杉酯碱（harringtonine，HT）对HL-60细胞凋亡的影响。

Low dose Ara C or harringtonine were given in 16 elderly patients and the CR rate was 22.2 % ( 4 / 18 ) .

小剂量阿糖胞苷（Arac）或三尖杉脂碱（H）化疗18例，CR率22.2%（418）。

Effects of lithium chloride and harringtonine on the differentiation , proliferation and c myc proto oncogene expression of HL 60 cells

锂和三尖杉酯碱对HL-60细胞增殖、分化和c-myc表达的影响

The main component analysis manifested that year even temperature and the highest temperature in a year are the main factors affecting the area difference of harringtonine and homoharringtonine content .

主成分分析结果表明年均温和年极高温是影响双酯碱含量地区差异的主要因子。

The inhibiting effect of harringtonine for sarcoma 180 in mice was 42.3 % at a dosage of 1mg / kg .

其中，三尖杉酯碱在1毫克/公升的剂量下，对小鼠肉瘤S（180）的抑制率为42.3%。

Low-dosage harringtonine treatment for Henoch-Schonlein nephritis

小剂量三尖杉酯碱治疗紫癜性肾炎

NMR spectroscopy methods were used to study the metabolic changes of ATP , PME and lipid during harringtonine ( HT ) induced apoptosis in HL-60 cell .

运用核磁共振波谱（NMR）研究三尖杉酯碱（HT）诱导人早幼粒白血病细胞（HL60）凋亡中三磷酸腺苷（ATP）、磷酸单脂（PME）及脂类的代谢变化。

The results showed that ( 1 ) harringtonine inhibited the growth and self-renewal of K562 cells in low concentration , and in high concentration it had a cytocidal effect ;

结果表明：①Harr在低浓度时即能有效地抑制K（562）细胞的增殖和自我更新能力，高浓度则呈显著细胞毒效应；

Low dose harringtonine ( LD-Harr ) combined with low dose cytarabine ( LD-Ara-c ) was used in treatment of 10 patients with ANLL .

小剂量三尖杉醋碱（LD-Harr）与小剂量阿糖胞苷（LD-Ara-c）联合治疗ANLL患者10例。

Therapeutic effects of H ( Harringtonine or Homoharringtonine ), HOC and HOAP were studied and compared in 140 patients with acute non-lymphoid leukemia .

本文比较了单用H、HOC加减及HOAP方案治疗急性非淋巴细胞性白血病140例的疗效。

Studies on the mechanism of inhibition of harringtonine on DNA synthesis ⅲ . the kinetics of inhibition of harringtonine and comparision of its derivatives for action on DNA polymerase α

三尖杉酯碱抑制脱氧核糖核酸生物合成机制的研究&Ⅲ.三尖杉酯碱抑制作用动力学及其衍生物作用的比较

Normal rats excreted 24.5 % of the administered radioactivity in the bile in 24 hours , while about 17.1 % was excreted as unchanged harringtonine .

静脉注射后24小时可自胆汁排出剂量的24.5%，其中原型药占17.1%。