HIV protease inhibitors

The research and development of HIV protease inhibitors and future perspectives

人类免疫缺陷病毒蛋白酶抑制剂的研究开发与展望

Clinical application and evaluation of HIV protease inhibitors

HIV蛋白酶抑制剂临床应用及评价

Effects of various HIV protease inhibitors on function of rat insulinoma cells

不同HIV蛋白酶抑制剂对鼠胰岛素瘤细胞功能的影响

Recent Advances in HIV Protease Inhibitors Application of Proteinase Inhibitor

HIV蛋白酶及其抑制剂蛋白酶抑制剂的应用进展

It is appropriate to the synthesis of lots of HIV protease inhibitors in principle .

该法原则上适用于多种HIV蛋白酶抑制剂的合成。

We summarized and reviewed the present status of characteristics , clinical efficacy and adverse reactions of HIV protease inhibitors .

本文对HIV蛋白酶抑制剂的特点、临床药效及不良反应的研究近况进行归纳总结并作此综述。

Progress in studies on nonpeptide HIV protease inhibitors

非肽类HIV蛋白酶抑制剂的研究进展

HIV protease inhibitors and apoptosis

HIV蛋白酶抑制剂与细胞凋亡

Objective HIV protease inhibitors are demonstrated to be effective drugs against the HIV infection The purpose of the present study is to establish a high throughput screening model by adopting fluorescent substrate and optimize such a system so as to be able to screen a large number of samples .

目的应用荧光方法建立、优化、评价艾滋病病毒1型（HIV-1）蛋白酶抑制剂高通量筛选模型，并用于大规模样品筛选。

Computeraided molecular design of HIV 1 protease dissociative inhibitors

HIV-1蛋白酶解聚型抑制剂的计算机辅助分子设计

This method is demonstrated by an example that sixteen virtual bio - active compounds were generated starting from HIV - 1 protease inhibitors pharmacophore in this work . The results of conformation analysis showed that the pharmacophore is contained in the favorite conformers of the generated structure .

经过对HIV-1蛋白酶抑制剂药效团进行虚拟活性化合物生成，得到了16个虚拟活性化合物，通过构象分析发现生成的化合物满足药效团的限制条件。