There were homology between HcoV-229E and porcine epidemic diarrhea virus , Canine coronavirus , Transmissible gastroenteritis virus , feline infectious peritonitis virus ;
HcoV229E与猪流行性腹泻病毒、犬冠状病毒、TGEV和猫感染性腹膜炎病毒有一定的同源性;