Germinal vesicle breakdown

Large amount of yolk granules deposit in the cytoplasm , and germinal vesicle breakdown occurs ;

第7阶段，卵母细胞中沉积大量卵黄，胚泡破裂；

Germinal vesicle breakdown ( GVBD ) and the first polar body extrusion were observed .

对照组直接用成熟培养液培养，观察其生发泡破裂（GVBD）和第一极体形成的过程。

It plays a pivotal role in the regulation of germinal vesicle breakdown ( GVBD ), chromatin condensation , spindle assembly and extrusion of the first polar body .

它在卵母细胞的生发泡破裂（GVBD）、染色体凝集、MⅠ期纺锤体组装和第一极体排放等过程中起着重要的调节作用。

Objective : To study the effects of endothelin-1 ( ET-1 ) on mouse oocyte germinal vesicle breakdown ( GVBD ) and extrusion of the first polar body ( PBI ) .

目的研究内皮素-1（ET-1）对小鼠未成熟卵母细胞生发泡破裂（GVBD）、第一极体（PBⅠ）排出的影响。

One hour after the injection of an ovulatory dose of HCG , expansion of cumulus cells in the outer layer of large antral follicles was observed , but oocyte maturation as evidenced by germinal vesicle breakdown ( GVBD ) was not evident .

注射HCG后1h，卵丘细胞开始扩展，此时卵母细胞核膜完整，即未发生生发泡破裂（GVBD）；

Results Arsenic could inhibit the extruding of the first polar body , reduce the quality and the viability of oocyte and lower the rate of IVF , but only little impact on the germinal vesicle breakdown ( GVBD ) and the number of oocytes after induction of ovulation .

结果As2O3对小鼠卵母细胞生发泡破裂、超排卵的卵母细胞数目没有影响，但可以抑制卵母细胞第一极体的释放，降低体外受精率和卵母细胞的存活率。