Genipin

Effect of temperature on crosslinking of collagen / chitosan scaffolds with genipin

交联温度对京尼平交联胶原/壳聚糖组织工程支架的影响

Genipin is also used as a kind of excellent natural biological crosslinking agent and widely used in the field of biological materials .

京尼平还是一种优良的生物交联剂，在生物材料领域被广泛应用。

Study on Reactivity of Genipin with Hide Collagen

京尼平与皮胶原的反应性研究

Non-toxic genipin is used as a crosslinker and it endows high strength and intrinsic fluorescence to the chitosan framework .

使用的无毒交联剂京尼平，赋予了复合支架材料特有的荧光特性和高的力学强度。

Genipin as a safe crosslinker further improved the mechanical properties and water resistance of the RC / CH films in the wet state .

京尼平作为一种安全的交联剂，进一步提高复合膜的力学性能和在水中的稳定性。

Objective To study the efficacy of autogenous morselized bone with gelatin and genipin for repair of radial bone defect in rabbit .

目的探讨以明胶和京尼平粘合自体颗粒骨修复新西兰大白兔桡骨缺损的效果，为临床应用提供依据。

RESULTS : ① The crosslinking index of genipin and glutaraldehyde crosslinked gelatin was 79.1 % and 52.3 % , respectively .

结果：①京尼平和戊二醛交联明胶材料的交联度分别为79.1%和52.3%。

Genipin crosslinked chitosan / alginate composite scaffold material has good biological characteristics . It is a very potential material in tissue engineering spinal cord field . 2 .

结论：1.京尼平交联的壳聚糖／藻酸盐复合支架材料，具有良好的生物学特性，为组织工程脊髓领域提供了非常具有潜力的材料。

Genipin also is a kind of excellent natural biological crosslinking agent , has the advantages at biocompatibility , cell low toxicity , resistance to degradation ability and application field widely .

它同时是一种优良的天然生物交联剂，具有生物相容性好、细胞毒性小、抗降解能力强和应用领域广泛等优点。

H-103 macroporous resin was used to separate genipin and the flow rate was 2 mL / min. The genipin was eluted by 60 % alcohol solution . The purity of genipin was 98.2 % , and the yield of genipin in the whole separation process reached 77.8 % .

选取H-103大孔树脂吸附京尼平，上柱液流速为2mL/min，以60%乙醇水溶液作为洗脱剂，经重结晶纯化后获得纯度达98.2%的京尼平，整个工艺收率为77.8%。