Fc fragment

Study on the Biologic Properties of Fc Fragment of Intravenous Immunoglobulin Preparations Produced in China

国内静注丙种球蛋白Fc段生物学功能研究

Preparation , characterization and application of monoclonal antibodies to Fc fragment of Ig fusion protein

抗Ig融合蛋白Fc段单克隆抗体的制备、鉴定与应用研究

Construction of eukaryotic expression vector of CD80-IgG1 Fc fragment fusion protein and its expression in CHO cells

CD80-IgG1Fc段融合蛋白真核表达载体的构建及表达

But it will be cleared rapidly in vivo and hard to identify in the absence of Fc fragment .

但它缺少Fc片段，在体内的半衰期短，很容易从血液中清除，而且在鉴定方面也存在困难。

Staphylococcal protein A ( SPA ) has an unique property of combining with the Fc fragment of IgG .

葡萄菌球A蛋白（SPA）能特异性地结合IgG分子的Fc片段而不影响IgG抗体对抗原的反应。

Conclusion The biologic activity of the Fc fragment may be preserved better in the low pH IVIG preparations than the neutral preparations .

结论低pHIVIG制品在保持IVIGFc段生物学活性方面可能比中性IVIG制品有更好的稳定性；

After the specific binding of antibody and antigen , the combination between its Fc fragment and Fc receptor of immune cells & C1q complement would be activated and strengthened .

当抗体与抗原特异结合后，其Fc段与免疫细胞Fc受体、C1q补体的结合得到了启动和加强。

Objective : The aim was to construct the recombinant of neuro related cell adhesion molecule ( NrCAM ) and immunoglobin Fc fragment and transfect it into insect cells .

目的：构建神经原相关的细胞粘附分子（NrCAM）和免疫球蛋白Fc片段融合基因的重组质粒并通过Baculovirus载体转染到昆虫细胞。

Validation analysis showed that ligation direction of the scFv gene of Pichia pastoris and the Fc fragment DNA was correct and was in agreement with the correct reading frame of scFv-Fc .

序列分析表明，scFv基因与Fc片段基因拼接正确，阅读框正确无误，表明成功构建了抗脂肪细胞40000特异膜蛋白scFv-Fc融合抗体毕赤酵母表达载体。

AIM : To prepare and characterize mAb to Fc fragment of Ig fusion protein , and to establish sandwich ELISA for detecting Ig fusion proteins and affinity chromatography method for Ig fusion protein purification .

目的：制备并鉴定抗Ig融合蛋白Fc段的单克隆抗体（mAb），建立用于检测Ig融合蛋白的夹心ELISA法和纯化Fc融合蛋白的亲和层析法。

A protein of Staphylococcus aureus ( Staphylococcal protein A , SPA ) could bind with the Fc fragment of people and a wide range of mammalian IgG molecules in serum , and the IgG retains its antigen binding capacity .

金黄色葡萄球菌A蛋白（staphylococcalproteinA，SPA）能与人及多种哺乳动物血清IgG分子中的Fc片段结合，结合后不影响抗体的活性。