Ebselen

CONCLUSION : The above results indicate that ebselen is effective against liver damage , which may derive from its anti lipid oxidation capacity .

结论：依布硒啉能保护肝损伤，可能与抗自由基的脂质过氧化有关。

Effects of ebselen and its analogue on arachidonic acid metabolism via lipoxygenase in rat platelets and peritoneal leukocytes

依布硒及其类似物对大鼠血小板和腹腔白细胞脂氧合酶产物生成的影响

The Ebselen of Intervention Effect for Pregnancy Lead Load

Ebselen对妊娠铅负荷干预

Test of stability and impurity and acute toxicity of Ebselen

依布哂啉的稳定性及杂质和急性毒性试验

Effect of ebselen on radiation - induced apoptosis

Ebselen对电离辐射诱发的细胞凋亡的影响

AIM : To study the protective effect of ebselen on anoxic damage of brain cells .

目的：研究依伯硒啉对神经细胞缺氧损伤的拮抗作用。

A Study fo the Effect of Ebselen on Hydroxyl Free Radical by ESR

Ebselen对羟基自由基作用的ESR研究

CONCLUSION : Ebselen can protect neurons from anoxic damage .

结论：依伯硒啉对神经元的缺氧损伤具拮抗作用。

Glutamate release increased by superoxide anion radical and the protection of ebselen

超氧阴离子对脑片谷氨酸释放的增强及依布硒的抑制

Studies on the anti-inflammatory activity of Ebselen and its analogues

Ebselen及其类似物的抗炎活性研究

Studies on Inhibition of Glutathione and Ebselen on Nitration of Insulin and Their Reaction Mechanism

谷胱甘肽和Ebselen对胰岛素硝化的抑制及其相互作用机理的研究

Inhibition and termination effect of ebselen and GSH on the oxidative modification of low density lipoprotein

Ebselen和谷胱甘肽对低密度脂蛋白氧化修饰的抑制和终止作用

Action of ebselen on brain tissue free radical metabolism induced by high-intensity and endurance-training in the rat

Ebselen对大强度耐力训练大鼠脑组织自由基代谢的影响

Protection of ebselen on oxygen free radical induced lipid peroxidation damage of cultured rat cortical neuron and cortical mitochondria

Ebselen对自由基诱发的皮层神经元和皮层线粒体脂质过氧化损伤的保护作用

Experiment Research on Free Radical Metabolism , and Cell Morphologic Effect of Some Tissues of High-intensity and Endurance-trained Rats Taken Ebselen

Ebselen对大强度耐力训练大鼠自由基代谢和部分组织细胞形态学影响的实验研究

Inhibition of Glutamate Uptake by Superoxide Anion Radical in Rat Cortical Synaptosomes and the Protective Effect of Ebselen

超氧自由基对谷氨酸摄取的抑制及Ebselen的保护

This suggests that ebselen has direct anti oxidant activity on neuron and its activity is not achieved by scavenging oxygen free radical .

因此，ebselen对氧自由基诱发的神经元脂质过氧化损伤有拮抗作用，这种作用与直接清除自由基无关。

Protection of Adriamycin-induced subacute cardio-toxicity by Ebselen

Ebselen对阿霉素致的心肌亚急性毒性损伤的保护作用

The protection against damage of DNA in renal cells of young rats by singlet oxygen with selenium compounds ( Na2SeO3 and ebselen ) has been investigated with the Kohn filtering method .

利用滤膜过滤法研究了硒化合物保护NIH小鼠肾细胞DNA免受~1O2损伤的作用；

Many scholar 's study shows that ebselen has obvious effect on the aspects of biology anti-oxidation and anti-inflammation . It also can control apoptosis and relieve the damnification of heart , liver and brain nerve caused by stimulation .

众多学者的研究表明，Ebselen在生物抗氧化、抗炎症方面作用疗效明显，且具有抑制细胞凋亡的作用，可以明显减轻刺激对心脏、肝脏、以及脑神经的损伤。

RESULTS The DSC analysis suggested that ebselen was present in an amorphorous form in the solid dispersion . Ebselen solid dispersion was prepared with water-soluble carriers pluronic , released 60 % in 60 min.

结果DSC分析表明，依布硒是以非晶体状态存在，用水溶性载体普朗尼克制备的分散体体外溶出60min大于60%。

In order to provide experiment basis for the use of ebselen in the sports medicine field , this experiment observes the free radical metabolism and cell morphologic effect of some tissues of high-intensity and endurance-trained rats taken ebselen .

本实验首次观察了Ebselen对大强度耐力训练大鼠自由基代谢以及部分组织细胞形态学方面的影响，旨在为Ebselen在运动医学领域的应用提供实验依据。