DNA-Binding Domain

Expression , purification and Crystallization of Human Heat Shock Transcription Factor 1 DNA-Binding Domain

人热休克蛋白转录因子1DNA结合结构域的表达、纯化和晶体生长

Construction and expression of DNA-binding domain plasmid with hepatitis B virus e antigen in yeast double hybrid system

乙型肝炎病毒e抗原基因作为酵母双杂交体系结合域载体的构建及表达

Short palindrome repeats are characteristic of DNA-binding domain of nuclear receptors .

短回文序列具有核受体的DNA结合域，调节核受体的表达。

Transcription factors were grouped into different families according to the type of DNA-binding domain that they encode .

根据与DNA结合的区域不同，转录因子分为若干个家族。

Probing Mg ~ ( 2 + ) Binding Site in p53 DNA-Binding Domain . A Molecular Dynamics Study

分子动力学方法探索镁离子在p53DNA结合域中的结合位点

Objective : To obtain heat shock transcription factor 1 ( HSF1 ) DNA-binding domain ( DBD ) and be used for X-ray diffraction experiments .

目的：获得大量热休克转录因子1（HSF1）DNA结合结构域（DBD）蛋白，用于晶体生长的三维结构解析。

The T-bet and other members of the T-box family are defined by the highly conserved T-box DNA-binding domain .

T-bet和其他T-box家族成员具有高度保守的T-boxDNA结合功能域。

Using pull-down and immunoprecipitation experiments , we show that DJ-1 is able to bind to p53 through its DNA-binding domain and C-terminus .

利用体外PullDown实验和体内的免疫共沉淀实验，我们发现DJ-1能够在细胞核内与p53的DNA结合区域及C末端相互结合。

Zinc finger nucleases ( ZFNs ) are artificial restriction enzymes made by fusing an engineered zinc finger DNA-binding domain to the DNA cleavage domain of a restriction enzyme .

锌指核酸酶是一种人工制做限制性内切酶，通过将锌指DNA结合区与限制性内切酶的DNA切割区融合获得。

The purpose of this study is to investigate the correlation between GC-resistance and the polymorphisms of GCR in DNA-binding domain and hormone-binding domain in children with PNS .

该文探讨儿童原发性肾病综合征对糖皮质激素治疗的效应与糖皮质激素受体DNA结合区、激素结合区基因多态性的相关性。

The structural features of TRs include four functional domains : A / B domain , DNA-binding domain , hinge region and ligand-binding domain . Each domain has its respective function . Referring to the self-guard mechanism of G.

其分子结构由4个功能区组成，分别是A/B区、DNA结合区域、铰链区和配体结合区域，每个区域都有其各自不同的功能。

C / EBP β is an important transcription factor that belongs to C / EBPs ( CCAAT enhancer binding proteins ) family , whose C-terminal region contains the highly conserved DNA-binding domain and dimerization domain .

C/EBPβ是转录因子C/EBPs（CCAATenhancerbindingproteins）家族的重要成员，其C端具有高度保守的DNA结合域和二聚化功能域。

Results The N terminal of AR contained an inhibitory domain located in an 81-amino acid segment lying upstream of the DNA-binding domain ( DBD ) . The inhibitory domain interacted directly with DBD and repressed DBD binding to the ARE .

结果：本研究发现AR的N-端含有一段有抑制功能的片段，它由81个氨基酸组成，位于DBD的上游，该片段能直接与DBD相互作用，抑制DBD与雄激素应答元件的结合。