血管内膜

B、C组血管内膜为单层内皮细胞，中膜平滑肌细胞排列整齐。

Intimal cell of B group was single layer , medial smooth muscle cells were in order .

B组、C组血管内膜改变较A组轻微。

The change of blood vessel intima in group B and group C was milder than that in group A.

目的建立兔血管内膜损伤性颈动脉粥样硬化模型，并探讨用临床应用型MRI检测动脉粥样硬化的形成过程。

Objective To establish endothelial injured carotid artery atherosclerosis model in rabbits and visualize the atherosclerosis formation process by MR imaging .

结果与A组比较，术后30天B组动脉壁无增厚、血管内膜未见明显增生；

Results Thirty days after transplantation , little intimal thickening and inflammatory cells infiltration in neointima and adventitia were showed in group B as well as group A.

家兔静脉移植桥血管内膜c-myc蛋白的表达

Expression of c-myc protein in vascular smooth muscle cell of vein graft rabbits

目的：研究局部应用反义寡核苷酸c－myc对自体静脉移植物内膜增生的防治作用，为反义技术防治血管内膜增生的早期临床应用提供实验依据。

Objective : To evaluate the inhibitory effect of antisense phosphorothioate c myc oligodeoxynucleotide on intimal hyperplasia in autogenous vein graft .

结论移植的EPCs可到达内膜损伤部位并参与损伤血管内膜的修复，降低新生内膜增殖。

Conclusion EPCs can arrive the injury intima and reduce neointima formation .

IH组血管内膜内可见连续性中断结构紊乱。

The vessel internal membrane of IH group is obviously discontinuity disorganization .

曲匹地尔可以抑制血管内膜的增生，并能明显阻抑各个时间点apoJmRNA和蛋白的表达。

Trapidil inhibited intimal proliferation and the expression of ApoJ mRNA and protein .

目的观察曲匹地尔对球囊损伤后血管内膜增生和基质金属蛋白酶-2（MMP-2）mRNA表达的影响，探讨其抑制内膜增生的可能机制。

Objective To evaluate the effect of trapidil on intimal proliferation and the expression of matrix metalloproteinase-2 ( MMP-2 ) mRNA in abdominal aorta after balloon injury .

颈动脉内膜-中膜厚度（IMT）是指颈动脉血管内膜和中膜之间的垂直距离。

The carotid intima-media thickness ( IMT ) refers to the vertical dimension between carotid intima and media .

血管内膜增殖细胞核抗原染色阳性细胞率与血小板衍生因子BB含量的相关系数为0.7127（P<0.01）。

Coefficient of linear correlation of PCNA with PDGF BB was 0.7127 ( P < 0.01 ) .

如能找到引导EPCs特异富集至受损血管内膜的相关分子，则可大大提高细胞移植效率。

If some kind of molecular can guide EPCs to the injured vessel specifically , the efficacy of cell implantation can be boosted .

三组动脉粥样硬化程度比较：益心舒组血管内膜厚度、内膜中膜厚度比值（I/Mthickness）均较高脂组明显减小（P0.05）。

Three degree of atherosclerosis in comparison : The intima thickness and intima-media thickness ratio ( I / M thickness ) of Yi Xin Shu Group were significantly reduced than the high-cholesterol group ( P0.05 ) . 3 .

目的观察动脉粥样硬化模型兔腹主动脉多普勒血流频谱，测量其血管内膜-中层厚度（IMT），探讨二者与动脉粥样硬化的相关性。

Objective To assess the correlation of intima media thickness ( IMT ) in two dimension ultrasound and hemodynamic parameters of Doppler with arteriosclerosis .

前列腺素E1对腹主动脉球囊损伤大鼠血管内膜、中膜增生及血浆相关因子水平的影响

Effects of prostaglandin E1 on the proliferation of tunica intima and media vasorum and the level of plasma related factors in rats with abdominal aortic endothelium injury

背景和目的：血管内膜增生是动脉血管对各种损伤的一种反应，也是动脉粥样硬化和经皮冠状动脉介入治疗（PercutaneousCoronaryIntervention，PCI）术后再狭窄的重要标志。

Background and Objective : Vascular intimal hyperplasia is a response of the arterial wall upon a wide range of stimuli . It is also a prominent hallmark of atherosclerosis and restenosis after percutaneous coronary intervention ( PCI ) .

虽有证据表明高浓度UA对血管内膜、内皮细胞、局部缺血缺氧组织等有损害作用，但确切的机制尚未十分明了。

There are few evidence that high UA could injure intima of vessel , endothelial cell and ischemia or hypoxia constitution , but the certain mechanism is not distinct .

目的：观察金雀异黄素（Genistein，Gen）局部灌注对动脉球囊损伤后不同时点平滑肌细胞增殖以及不同时点血管内膜增殖的影响，探讨Gen局部应用对预防再狭窄的意义。

Objective : To evaluate the preventive effect of genistein by regional perfusion in intimal thickening and VSMCs proliferation and to research the restenosis-preventing mechanism of genistein after balloon angioplasty .

目的研究主动脉球囊损伤后，csis原癌基因反义寡核苷酸（AODN）局部干预对血管内膜增生的影响。

Objective To study the inhibitory effect of locally delivered C sis proto oncogene antisense oligodeoxynucleotides ( AODN ) via balloon catheter on intimal injury following balloon angioplasty in rabbit aorta .

（HC+S）组的AS斑块面积及血管内膜厚度均大于NC组（P<0.05），但小于HC组（P<0.05）。

The aortic plaque acreage and intimal thickness in the ( HC + S ) group were significantly higher than those in the NC group , but significantly lower than those in the HC group ( P < 0.05 ) .

结论ITI和IMR是对移植血管内膜增生程度进行分级的敏感方法。

Conclusion The IH indexes ( ITI , IMR ) are very sensitive tools to grade the degree of IH in the graft vessels .

VAF转化为MF后向血管内膜迁移，增殖，成为新生内膜的细胞成分。

When the VAF cells transformation into MF , it begins to migrate to endomembrane , and proliferate , to become cell component of the new endomembrane .

结果91.5%冠心病人和100%心肌梗死病人存在血管内膜-中层（IMT）增厚，斑块和管腔狭窄等变化。

Results Patients in 91 . 5 % of coronary heart disease and the 100 % of the myocardial infarction disease showed the evident increase in IMT , plaque and stenosis in carotid artery .

此干预方式使用1.0V电压刺激即可灼伤血管内膜。

With the stimulation of just 1.0V voltage , the vascular intima could be burned by this kind of intervention .

方法对5只大白兔采用2F球囊导管伸入一侧颈动脉内行内膜毁损术，造成血管内膜增生、管腔狭窄。

Methods A 2 F Foley 's tube was inserted into unilateral carotid artery for performing intimal injury in 5 rabbits , and causing intimal hyperplasia and angiostenosis .

方法在兔腹主动脉球囊损伤的模型上，光镜下观察血管内膜增生情况及应用RT-PCR的方法观察MMP-2、TIMP-2在球囊损伤后不同时间的表达情况；

Methods On the model of balloon injury of rabbit aortic artery , the change of intimal proliferation was observed under optical microscopy and the time course of MMP-2 and TIMP-2 mRNA level was examined with the method of RT-PCR .

结果：白藜三醇高剂量可有效地抑制血管内膜的增生，使内膜增生指数从模型组（M组）的0.41降低到白藜三醇高剂量组（H组）的0.28（P0.01）；

Results : At the higher concentration of resveratrol ( H group ), the intimal hyperplasia of injuried vascular wall was effectively inhibited ; the intimal proliferation index was significantly less than that in the untreated model group ( M group ) ( 0.28 vs 0.41 , P0.01 );

结果模型组、正义组、Scramble组的血管内膜面积、中膜面积、内膜/中膜在第5d增加，14d达到高峰；

Results In model group , sense group and scramble group , the vessel intima area , media area and the intima / media ratio increased after 5d and reached the maximum after 14d .

结果：大鼠灌服硫酸氯吡格雷1,3,10mg/kg后，明显抑制ADP、花生四烯酸及胶原诱导的血小板聚集，明显延长电流损伤血管内膜所致实验性动脉血栓形成时间，抑制动静脉旁路丝线上血栓的生成；

Result : Clopidogrel significantly inhibit ADP , AA , collagen induced platelet aggregation , prolong thrombus formation time induced by electrical stimulation , reduced thrombus weight in arteriovenous shunt at oral doses 1,3,10mg / kg in rats ;