螺环

建立了血浆样品中盐酸丁螺环酮的气相色谱质谱（GCMS）联用的定量分析方法。

A method for the quantitative determination of buspirone in plasma was developed by means of GC-MS with selected ion and qualifier ion monitoring .

采用示差扫描量热法（DSC）对螺环原碳酸酯膨胀单体（SOC）/双酚A型环氧树脂（EP）体系的固化行为、放热峰进行了分析；

Curing behaviors and exothermic peaks of spiro orthocarbonate / epoxy resin system were discussed by DSC ( differential scanning calorimetry ) .

结论丁螺环酮治疗能显著改善IBS患者的精神和躯体两方面的症状。

Conclusions Buspirone could improve the patients with irritable bowel syndrome significantly both in the spiritual and somatic symptoms .

研究了螺环磷酸酯阻燃剂、齐聚物型磷酸酯阻燃剂和有机磷膨胀型阻燃剂在PP、PVC、PU利PET无纺布中的应用。

The application of spirocyclic phosphates , phosphate oligomers and organophosphorous intumescent fire-proofing agents in PP , PVC , PU and nonwoven fabrics of PET were studied .

应用小鼠一次性被动回避和穿箱主动回避行为法，观察抗焦虑剂丁螺环酮（Bus）对学习获得和记忆保持的影响。

To study the effects of buspirone , a selective anxiolytic drugs , on acquisition and retention , mice were trained and tested on step through passive avoidance and two way active avoidance learning tasks .

用丁螺环酮和安慰剂治疗IBS患者，疗程8周，治疗后第4、8周再次评分。

The course of treatment was eight weeks and the patients were assessed with scale for Hamilton anxiety scale ( HAMA ) in 0,4 and 8 weeks .

一种新螺环单体的合成及对F-44的改性研究

Synthesis of a new spiro orthocarbonate and its modification on F-44 phenolic epoxy

结果和安慰剂组比较，IBS患者接受丁螺环酮治疗8周后，精神和躯体症状有明显改善。

Results Compared with dummy , the condition of patients with irritable bowel syndrome were improved obviously both in the spiritual and somatic symptoms after the 8 weeks ' treatment with buspirone .

重新研究了Lewis酸催化的甾体皂甙元E/F螺环乙酰化开环反应，并通过波谱分析和单晶X衍射修正了原指定结构。

Lewis acid catalyzed acetylation of steroidal sapogenin was reinvestigated , and the previous assigned structures A , B and C of E / F ring opening products were rectified as 1 , 2 and 3 according to X ray diffraction analysis .

方法采用离体动物口腔粘膜的体外渗透试验方法，比较盐酸丁螺环酮对家兔、豚鼠、猪、羊和牛的口腔粘膜渗透性，考察药物浓度及溶液pH值的影响。

METHODS The in vitro penetration model was designed to investigate drug buccal mucosa permeability , and the influence factors ( different animal oral mucosa , such as rabbit , guinea pig , pig , sheep and cow , drug concentrations and solution pH values ) were measured .

结果表明BPR-HPMC缓释片具备了缓释制剂的某些特点，比如盐酸丁螺环酮体外持续释放达24h，该缓释片存在的缺点是在2h之前药物释放太快。

This matrix system ( BPR-HPMC extended release Tablets , BPR-HPMC ) shows some characterization of extended-release , for example , Buspirone Hydrochloride release in vitro 24 for hours .

方法：1369例焦虑性障碍的患者口服丁螺环酮治疗4周，剂量5～60mg，在治疗前后进行HAMD评定。

Methods : 1 369 anxiety disorders patients were treated with buspirone 5 ~ 60mg · d - 1 for 4 week . All the patients were evaluated by HAMD before and after treatment .

以氯化螺环磷酸酯和双酚A为原料，乙腈为溶剂，三乙胺为缚酸剂和催化剂，在回流条件下反应6h合成了氯化螺环磷酸酯-双酚A共聚物，收率833%。

Flame retardant of copolymer was synthesized in 83.3 % yield by the reaction of spirocyclic pentaerythritol di ( phosphate monochloride ) with bisphenol A using acetonitrile as solvent and triethylamine as catalyst and acid acceptor under refluxing for 6 h.

结果：与阳性药丁螺环酮（5HT1A受体部分激动剂）类似，CTN及CTN4,7,8,9,10均可剂量依赖性激活突触膜AC，其中CTN8在5个黄酮类单体中活性最强。

Results : Just like the positive drug buspirone , a 5-HT 1A receptor partial agonist , CTN and its five flavonoid compounds all activated AC in synaptic membrane in a dose-dependent manner , with compound CTN-8 being the most effective .

新化合物1为首次从微生物中报道的14β-15-酮甾醇，化合物30-34为天然罕见的杂螺环fumitremorgin类生物碱。

New compound 1 was one of rare 14 β sterols and first reported from microorganism , and new compounds 30-34 were rare spiro-oxindole fumitremorgin-type alkaloids from nature .

盐酸丁螺环酮对脑卒中后情感障碍及神经功能的影响

Effects of buspirone hydrochloride on post-stroke affective disorder and neural function

盐酸丁螺环酮对动物口腔粘膜的渗透性及其机理

Permeation of buspirone hydrochloride across animal buccal mucosa and its mechanism

舍曲林与丁螺环酮治疗广泛性焦虑的对照研究

Comparative Study on Treatment of Generalized Anxiety with Sertraline and Buspirone

丁螺环酮对小鼠主动和被动回避反应的影响

Effects of buspirone on active and passive avoidance responses in mice

目的：对抗抑郁剂合用丁螺环酮治疗抑郁的疗效进行临床研究。

Objective : To explore the additional efficacy of buspirone on antidepressant .

螺环原碳酸酯类膨胀单体的合成

Synthesis of Spiro Orthocarbonate , a Kind of Expansion Monomer

盐酸丁螺环酮临床药代动力学及生物利用度研究

Studies on pharmacokinetics and bioavailability of buspirone hydrochloride in human

丁螺环酮与阿米替林治疗抑郁症80例双盲对照观察

A Double-blind Controll Trial of Buspirone and Amitriptyline in 80 Cases Depression

目的探讨丁螺环酮对抗抑郁剂的增效作用。

Objective To explore the add-effect of Buspirone to antidepressants .

西酞普兰联合丁螺环酮治疗老年期抑郁症

Combination treatment of citalopram with buspirone for elderly depressive patients

螺环原碳酸酯的单体合成及阳离子聚合

Synthesis and cationic polymerization of a new spiro orthocarbonate monomer

一种新型螺环原碳酸酯共聚改性环氧树脂的研究

Study on Epoxy Resin Modified by Copolymerizing with a New Spiro Ortho Carbonate

一锅法合成螺环二醇芳并呋喃类化合物的&锅化合成法

One - pot Synthetic Method of The Benzofuran Compounds

所生产的螺环二醇具有增加的粒度。

The spiroglycol produced has an increased particle size .

目的观察丁螺环酮对改善脑卒中后共济失调症状的临床疗效。

Objective To observe the effect of buspirone on ataxia symptom after stroke .